The Effect of Placental Cord Drainage on Postpartum Blood Loss

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

71 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-12

Study Completion Date

2023-06-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To determine if placental cord drainage decreases the blood loss after spontaneous vaginal delivery

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Comparison Between Cervical Tourniquet and Uterine Artery Ligation Prior to Segmental Resection Approach

NCT06483724

Placenta Accreta Spectrum

NOT_YET_RECRUITING NA

Placental Cord Drainage After Vaginal Delivery

NCT03487341

Blood Loss

COMPLETED NA

Placental Perfusion in the Entire Placenta and With Sonobiopsy by Ultrasound

NCT05245279

Placenta Diseases

COMPLETED NA

Bilateral Uterine Artery Ligation After Intrapartum or Postpartum Hemorrhage on Ovarian Reserve Markers and Pregnancy Outcome

NCT05647538

Bilateral Uterine Artery Ligation Intrapartum or Postpartum Hemorrhage Ovarian Reserve Markers +1 more

COMPLETED

Retrospective Study of 110 Cases of Uterine Rupture to Determine Obstetric and Neonatal Complications

NCT03052686

Anomaly Uterus

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Postpartum hemorrhage complicates 3% of pregnancies in the United States and is a leading cause of maternal morbidity and mortality. ACOG defines PPH as cumulative blood loss greater than 1000cc; however a blood loss \>500cc should be considered abnormal. Primary PPH occurs in the first 24 hours and is largely secondary to uterine agony. ACOG as well as the WHO recommend active management of the third stage of labor to prevent PPH. This includes oxytocin administration, uterine massage, and gentle cord traction. Placental cord drainage (PCD) is the unclamping of the umbilical cord to allow for drainage of the blood from the placenta. It is another technique used to shorten the third stage of labor; however, it has not been well studied

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postpartum Hemorrhage

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Placenta Blood Drained Placenta Blood Not Drained

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placenta Blood Drained

Immediately after delayed cord clamping and cutting of the umbilical cord, the cord will be unclamped and blood with be drained until cessation of flow.

Group Type EXPERIMENTAL

Placental Blood Drainage

Intervention Type PROCEDURE

Immediately after vaginal delivery following delayed cord clamping and cutting of the cord, the cord will be unclamped and blood will be drained from the placenta until cessation of flow.

Placenta Blood Not Drained

This is the control group. The cord will not be unclamped.

Group Type ACTIVE_COMPARATOR

Placenta Blood Not Drained

Intervention Type PROCEDURE

Placenta Blood Not Drained

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Placental Blood Drainage

Immediately after vaginal delivery following delayed cord clamping and cutting of the cord, the cord will be unclamped and blood will be drained from the placenta until cessation of flow.

Intervention Type PROCEDURE

Placenta Blood Not Drained

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Singleton Gestation
* Ages 18-45
* English Speaking
* Third Trimester Gestation

Exclusion Criteria

* Operative Vaginal Delivery
* Multiple Gestation
* Cesarean Delivery
* Episiotomy
* 3rd or 4th degree laceration
* Less than the Third Trimester of Pregnancy
* Chorioamnionitis
* History of Postpartum Hemorrhage
* Macrosomic Infant

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes