Uterine Artery Ligation to Decrease Blood Loss With Central Placenta Previa

NCT ID: NCT02002026

Last Updated: 2016-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2014-11-30

Brief Summary

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This trial will address the effect of uterine artery ligation during Cesarean section in cases with placenta previa to decrease blood loss.

Detailed Description

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This Study will address the effect of uterine artery ligation prior to fetal delivery during Cesarean section in cases with central placenta previa to guard against postpartum hemorrhage and to minimize blood loss.

Conditions

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Placenta Previa Without Hemorrhage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Ligation group

Uterine artery ligation will be done for patients in this group

Group Type ACTIVE_COMPARATOR

Uterine artery ligation

Intervention Type PROCEDURE

Uterine artery ligation during cesarean section before delivery of the baby

Control group

Conventional CS

Group Type PLACEBO_COMPARATOR

Uterine artery ligation

Intervention Type PROCEDURE

Uterine artery ligation during cesarean section before delivery of the baby

Interventions

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Uterine artery ligation

Uterine artery ligation during cesarean section before delivery of the baby

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Placenta previa is diagnosed when the lowest placental edge is located within 5 cm of the internal os at ultrasound
* Symptomatic Placenta previa with at least one episode of bleeding
* Estimated gestational age within 28 to 40 weeks
* Maternal age \> 18 years
* Informed consent
* Social affiliation

Exclusion Criteria

* Premature rupture of membranes
* Severe bleeding.
* Abnormal fetal heart rates.
* Pre-eclampsia, chorioamnionitis, severe chronic renal disease.
Minimum Eligible Age

18 Years

Maximum Eligible Age

49 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Minia Maternity University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Ahmad Sameer Sanad

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmad S Sameer, MD

Role: PRINCIPAL_INVESTIGATOR

Minia Maternity University Hospital

Locations

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Minia Maternity University Hospital

Minya, Minya Governorate, Egypt

Site Status

Countries

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Egypt

References

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Sanad AS, Mahran AE, Aboulfotouh ME, Kamel HH, Mohammed HF, Bahaa HA, Elkateeb RR, Abdelazim AG, El-Din MAZ, Shawki HE. The effect of uterine artery ligation in patients with central placenta pevia: a randomized controlled trial. BMC Pregnancy Childbirth. 2018 Aug 29;18(1):351. doi: 10.1186/s12884-018-1989-5.

Reference Type DERIVED
PMID: 30157787 (View on PubMed)

Other Identifiers

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U1111-1150-4666

Identifier Type: -

Identifier Source: org_study_id

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