Comparison of Myocardial Infarction Patients Who Were Prescribed a Novel Antiplatelet Agent or Clopidogrel

NCT ID: NCT05599152

Last Updated: 2022-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-21

Study Completion Date

2022-11-30

Brief Summary

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Myocardial infarction is defined according to icd-10 using the data base of South korea National Health Insurance Corporation, where personal identification information has already been removed, and detailed results are derived for each drug category.

Detailed Description

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The purpose of this study is to compare the prognosis of patients with clopidogrel after early discontinuation of ticagrelor/prasugrel with patients who maintained aspirin and ticagrelor/prasugrel as standard therapy in patients with acute myocardial infarction who underwent percutaneous coronary intervention.

Conditions

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Myocardial Infarction

Keywords

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clopidogrel novel antiplatelet agent

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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ticagrelor/prasugrel Group

Patients with acute myocardial infarction who underwent percutaneous coronary intervention and maintained aspirin and ticagrelor/prasugrel as standard therapy.

No interventions assigned to this group

clopidogrel Group

In patients with acute myocardial infarction who underwent percutaneous coronary intervention, discontinued ticagrelor/prasugrel and switched to clopidogrel

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who have a diagnosis code for acute myocardial infarction indicated in the National Health Insurance data and data for drugs that have used ticagrelor/prasugrel for 30-90 days when hospitalized for the relevant disease.
* Patients who switched to clopidogrel after 30-90 days.
* Patients with a diagnosis code for Venus myocardial infarction and a prescription code for percutaneous cardiovascular intervention in the National Health Insurance data.
* Adults 18 years of age or older

Exclusion Criteria

* A person who has data for requesting blood transfusion during the period of hospitalization in the National Health Insurance data
* Those who have data for oral anticoagulants (warfarin, Coumadin, apixaban, edoxaban, dabigatran, rivaroxaban) in the National Health Insurance data
* Those who have a diagnosis code for malignant tumor in the National Health Insurance data
* Those who have end-stage renal failure code in the National Health Insurance data or those who have data for hemo/peritoneal dialysis
* A person who has a request for blood transfusion during the period of using Ticagrelor/prasugrel
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chong Kun Dang Pharmaceutical

INDUSTRY

Sponsor Role collaborator

Chan Joon Kim

OTHER

Sponsor Role lead

Responsible Party

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Chan Joon Kim

professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Chan Joon Kim

Role: PRINCIPAL_INVESTIGATOR

The Catholic University of Korea, Uijeongbu ST. Mary's Hospital

Locations

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The Catholic University of Korea, Uijeongbu ST. Mary's Hospital

Uijeongbu-si, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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UMT aPM

Role: CONTACT

Phone: 010-8622-9502

Email: [email protected]

Facility Contacts

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UMT

Role: primary

Other Identifiers

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CKD-HIRA-Data-Review

Identifier Type: -

Identifier Source: org_study_id