Behavioral Parenting Skills As A Novel Target for Improving Pediatric Medication Adherence

NCT ID: NCT05587582

Last Updated: 2025-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

51 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2025-01-07

Brief Summary

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This study observes behavioral parenting skills to see whether it could be a novel target for improving pediatric medication adherence. This study may help researchers better understand the challenges parents face when giving their young child with an illness medicine at home and learn about various factors related to medication compliance in young children

Detailed Description

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PRIMARY OBJECTIVES:

I. Use direct observation of medication administration in the home to understand common episode-level barriers and identify the most impactful behavioral parenting skills for intervention.

II. Use daily diary methods to identify contextual barriers to adherence and identify intervention components to help parents anticipate barriers and plan strategies to promote successful adherence.

OUTLINE:

Participants complete a survey over 15-20 minutes at baseline. Family behaviors before, during and after the administration of medication to the child are video-recorded over 40-45 minutes. Participants receive MEMS electronic pill bottle to use for 2 weeks and complete daily survey over 5 minutes for 14 days.

Conditions

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Acute Lymphoblastic Leukemia

Study Design

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Observational Model Type

FAMILY_BASED

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Observational (Family Behaviors)

PRIMARY OBJECTIVES:

I. Use direct observation of medication administration in the home to understand common episode-level barriers and identify the most impactful behavioral parenting skills for intervention.

II. Use daily diary methods to identify contextual barriers to adherence and identify intervention components to help parents anticipate barriers and plan strategies to promote successful adherence.

OUTLINE:

Participants complete a survey over 15-20 minutes at baseline. Family behaviors before, during and after the administration of medication to the child are video-recorded over 40-45 minutes. Participants receive MEMS electronic pill bottle to use for 2 weeks and complete daily survey over 5 minutes for 14 days.

Survey Administration

Intervention Type OTHER

Complete a survey

Interventions

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Survey Administration

Complete a survey

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Parent of a child diagnosed within the past month with acute lymphoblastic leukemia (ALL)
* Pediatric patient's age 3 - 9.

\* If present during the home visit, any other child, ages 0-18
* Child on therapy that includes oral mercaptopurine (6-MP) administration
* Parent age 18 - NA (No Limit)
* Parent should have verbal English fluency
* Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure
* The following special populations may be included in this study:

* Pregnant women: due to the design of this behavioral research, pregnant and fetuses should incur no elevated risk from participation.

Children under age 18 will participate in one aspect of the study, the video recording of medication administration.

\* Other children (not the pediatric patient) under age 18 that are present during the time of the home visit

Exclusion:

* Pediatric patient is on therapy that does not include oral 6-MP administration
* Cognitively impaired adults/adults with impaired decision-making capacity
* Pediatric patients who are not yet adults (infants under the age of 3, children over 9 years, teenagers)
* Prisoners
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Roswell Park Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Elizabeth Bouchard, PhD

Role: PRINCIPAL_INVESTIGATOR

Roswell Park Comprehensive Cancer Center

Locations

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Roswell Park Cancer Institute

Buffalo, New York, United States

Site Status

Countries

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United States

Other Identifiers

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R01CA258337

Identifier Type: NIH

Identifier Source: secondary_id

View Link

I 1832021

Identifier Type: -

Identifier Source: org_study_id

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