Trial Outcomes & Findings for COVID-19 Testing and Vaccine Literacy for Women With Criminal Legal System Involvement (NCT NCT05582746)

NCT ID: NCT05582746

Last Updated: 2025-01-30

Results Overview

Nine multiple-choice items developed by study team and corresponding to intervention content, which regarding COVID-19 transmission, risk, mitigation, vaccine risk, and testing in a pandemic environment . The sum of scores on all 9 items has a possible total score ranges from 0 (minimum) to 9 (maximum), a higher score represents a higher level of COVID-19 testing and vaccine knowledge (i.e., better outcome).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

295 participants

Primary outcome timeframe

Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Results posted on

2025-01-30

Participant Flow

Participant milestones

Participant milestones
Measure
COVID-19 mHealth Intervention
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
Baseline
STARTED
295
Baseline
COMPLETED
295
Baseline
NOT COMPLETED
0
1-month Follow-up
STARTED
295
1-month Follow-up
COMPLETED
265
1-month Follow-up
NOT COMPLETED
30
12-month Follow-up
STARTED
265
12-month Follow-up
COMPLETED
235
12-month Follow-up
NOT COMPLETED
30

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

There were n=10 (3.4%) missing for age.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
Age, Continuous
45.8 years
STANDARD_DEVIATION 11.5 • n=285 Participants • There were n=10 (3.4%) missing for age.
Sex: Female, Male
Female
295 Participants
n=295 Participants
Sex: Female, Male
Male
0 Participants
n=295 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
27 Participants
n=295 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
256 Participants
n=295 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
12 Participants
n=295 Participants
Race/Ethnicity, Customized
Race · Black or African American
172 Participants
n=295 Participants
Race/Ethnicity, Customized
Race · White
94 Participants
n=295 Participants
Race/Ethnicity, Customized
Race · Other People of Color
24 Participants
n=295 Participants
Race/Ethnicity, Customized
Race · Unknown or not reported
5 Participants
n=295 Participants
Region of Enrollment
United States
295 participants
n=295 Participants
Education
Less than High School
59 Participants
n=295 Participants
Education
High School or higher
227 Participants
n=295 Participants
Education
unknown or not reported
9 Participants
n=295 Participants
Insurance
Yes
244 Participants
n=295 Participants
Insurance
No
36 Participants
n=295 Participants
Insurance
unknow or not reported
15 Participants
n=295 Participants
Employment
Yes
111 Participants
n=295 Participants
Employment
No
168 Participants
n=295 Participants
Employment
Unknown or not reported
16 Participants
n=295 Participants
City
Kansas City
51 Participants
n=295 Participants
City
Birmingham
88 Participants
n=295 Participants
City
Oakland
156 Participants
n=295 Participants

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: There is missing data due to no response, measures reported are reported before multiple imputation for missingness (i.e., only complete cases).

Nine multiple-choice items developed by study team and corresponding to intervention content, which regarding COVID-19 transmission, risk, mitigation, vaccine risk, and testing in a pandemic environment . The sum of scores on all 9 items has a possible total score ranges from 0 (minimum) to 9 (maximum), a higher score represents a higher level of COVID-19 testing and vaccine knowledge (i.e., better outcome).

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
COVID-19 Testing and Vaccine Knowledge
Pre-intervention assessment
3.58 score on a scale
Standard Deviation 1.36
COVID-19 Testing and Vaccine Knowledge
1-month assessment
3.98 score on a scale
Standard Deviation 1.36
COVID-19 Testing and Vaccine Knowledge
12-month assessment
3.85 score on a scale
Standard Deviation 1.39

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: There is missing data due to no response, measures reported are reported before multiple imputation for missingness (i.e., only complete cases).

General COVID-19 Mistrust Scale (PMID: 33196555) Adopted 4-items COVID-19 Mistrust Scale, which focus on public information advanced by the government and public health care providers. Each item was on 5-point Likert Scare range from 1 (strongly disagree) to 5 (strongly agree). A mean score of 4 items represent participants' mistrust level towards government and public health care providers, which ranges from 1 (minimum) to 5 (maximum). A higher score means a higher mistrust score (i.e., worse outcome).

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
COVID-19 Mistrust Score
Pre-intervention assessment
3.25 score on a scale
Standard Deviation 1.21
COVID-19 Mistrust Score
1-month assessment
3.09 score on a scale
Standard Deviation 1.16
COVID-19 Mistrust Score
12-month assessment
3.21 score on a scale
Standard Deviation 1.08

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Self-reported perceived accessibility of COVID-19 testing. A 5-point Likert scale item ranges from 1 (strongly disagree) to 5 (strongly agree). A higher score represent participants' higher level of perceived accessibility (i.e., a better outcome).

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
COVID-19 Testing Accessibility - Ease of Access
Pre-Intervention assessment
4.36 score on a scale
Standard Deviation 1.03
COVID-19 Testing Accessibility - Ease of Access
1-month
4.51 score on a scale
Standard Deviation 0.89
COVID-19 Testing Accessibility - Ease of Access
12-month
4.49 score on a scale
Standard Deviation 0.96

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: There is missing data due to no response, measures reported are reported before multiple imputation for missingness (i.e., only complete cases).

Self-reported confidence level of locating the place to get COVID-19 testing. A 5-point Likert scale item ranges from 1 (strongly disagree) to 5 (strongly agree). A higher score represent participants' higher level of confidence (i.e., a better outcome).

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
COVID-19 Testing Accessibility - Confidence to Locate
Pre-Intervention assessment
4.42 score on a scale
Standard Deviation 1.05
COVID-19 Testing Accessibility - Confidence to Locate
1-month assessment
4.54 score on a scale
Standard Deviation 0.95
COVID-19 Testing Accessibility - Confidence to Locate
12-month assessment
4.49 score on a scale
Standard Deviation 0.96

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: There is missing data due to no response, measures reported are reported before multiple imputation for missingness (i.e., only complete cases).

Percentage of participants' aware the government program that offers free tests through the mail.

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
COVID-19 Testing Accessibility - Free Access
1-month assessment
221 Participants
COVID-19 Testing Accessibility - Free Access
12-month assessment
195 Participants
COVID-19 Testing Accessibility - Free Access
Pre-Intervention assessment
209 Participants

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: There is missing data due to no response, measures reported are reported before multiple imputation for missingness (i.e., only complete cases).

Count number of participants who indicated they ever had COVID-19 testing.

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
Ever Had COVID-19 Testing
Pre-Intervention assessment
264 Participants
Ever Had COVID-19 Testing
1-month assessment
253 Participants
Ever Had COVID-19 Testing
12-month assessment
229 Participants

PRIMARY outcome

Timeframe: Pre-Intervention assessment measured at baseline, Post-intervention assessment measured at 1-month and 12-month follow-ups.

Population: There is missing data due to no response, measures reported are reported before multiple imputation for missingness (i.e., only complete cases).

Count number of participants who indicated they ever had COVID-19 vaccine.

Outcome measures

Outcome measures
Measure
COVID-19 mHealth Intervention
n=295 Participants
We are using a pre-post study design, given the low risk of the educational intervention and expected benefit. All participants received an mHealth intervention to boost COVID-19 testing and vaccine literacy, access, and uptake among women with CLSI in three cities.
Ever Received COVID-19 Vaccine
Pre-Intervention assessment
191 Participants
Ever Received COVID-19 Vaccine
1-month assessment
182 Participants
Ever Received COVID-19 Vaccine
12-month assessment
165 Participants

Adverse Events

COVID-19 mHealth Intervention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 3 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Jason E Glenn

University of Kansas Medical Center

Phone: 9135880076

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place