Sarcopenia After Bariatric Surgery in Older Patients: a Cohort Study

NCT ID: NCT05582668

Last Updated: 2025-02-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-10-03

Study Completion Date

2024-07-14

Brief Summary

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The retrospective cohort study will compare the prevalence of sarcopenia and associated factors between older patients who have undergone bariatric surgery and older patients with obesity without previous bariatric surgery.

Detailed Description

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The aim of the study is to compare the prevalence of sarcopenia and nutritional status between adults older than 65 years who have previously undergone bariatric surgery and patients with obesity but without previous bariatric surgery. Current sarcopenia will be assessed during a cross-sectional assessment after surgery using the criteria from the European Working Group on Sarcopenia in Older People (EWGSOP).

Conditions

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Overweight and Obesity Bariatric Surgery Aging Sarcopenic Obesity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Cohort 1

Cohort 1: Older patients with overweight, obesity after bariatric surgery

Bariatric surgery

Intervention Type PROCEDURE

Bariatric surgery

Cohort 2

Cohort 2: Older patients with overweight, obesity without bariatric surgery

No interventions assigned to this group

Interventions

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Bariatric surgery

Bariatric surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Signed informed consent
* Age 65 years or older
* Cohort 1 (exposed): Previous bariatric surgery for obesity at least 1 one year ago
* Cohort 2 (unexposed): No previous weight loss surgery

Exclusion Criteria

* Current diagnosis of cancer
* Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Stage 3, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage 4.
* Immobility
* Neuromuscular degenerative conditions
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitaire Ziekenhuizen KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Obesity Clinic University Hospitals Leuven

Leuven, , Belgium

Site Status

Countries

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Belgium

References

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Eksteen G, Vanuytsel T, Vangoitsenhoven R, Mertens A, Lannoo M, De Leus E, Van der Schueren B, Matthys C. Sarcopenia, Muscle Mass and Protein Intake in Adults Older Than 65 Years After Earlier Bariatric Surgery. J Cachexia Sarcopenia Muscle. 2025 Jun;16(3):e13839. doi: 10.1002/jcsm.13839.

Reference Type DERIVED
PMID: 40468919 (View on PubMed)

Other Identifiers

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S66815

Identifier Type: -

Identifier Source: org_study_id

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