Surgical Management and Outcome of Tethered Cord Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

35 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-11-02

Study Completion Date

2024-12-02

Brief Summary

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The aim of this study is to assess surgical management and outcome of Tethered cord syndrome

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Detailed Description

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Tethered cord syndrome (TCS) is a developmental abnormality of the neuroaxis which is usually diagnosed in childhood. The actual tethering has been attributed to a variety of pathologic entities, including a thickened tight filum terminale , intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and adherence of the neural placode following previous closure of a myelomeningocele. However, sufficient differences in the mode of onset, clinical manifestations, and outcome exist between pediatric and adolescent patients with tethered cord to warrant a more detailed analysis of the adult syndrome. The most problematic technical consideration in surgery for the release of the tethered cord is how to preserve functioning neural elements and rebuild the dural sac to avoid CSF leak. The purpose of this study is to review causes of Tethered cord, clinical presentation, diagnostic tools, treatment options and outcome in school-aged children, adolescents, and young adults with Tethered cord.

Conditions

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Tethered Cord Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Detethering of the spinal cord

Release of the tethered spinal cord

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with Tethered cord syndrome presenting at our institute
* Patients with spinal dysraphism
* Lipomyelomeningocele with Tethered cord
* patients presented with neurological deficit after lipomyelomeningocele repair due to Tethered cord
* patients presented with neurological deficit after myelomeningocele repair due to Tethered cord
* Diastematomyelia with Tethered cord - Tethered cord due to filum terminale.
* Tethered cord due to fibrous adhesions