rTMS in the Prevention and Treatment of Postoperative Executive Dysfunction
NCT ID: NCT05575583
Last Updated: 2023-03-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
400 participants
INTERVENTIONAL
2022-11-30
2025-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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Intervention group
Subjects underwent repetitive transcranial magnetic stimulation for five consecutive days from day 2 to day 6 after surgery. The stimulation target area was the posterior cingulate gyrus, and the neuronavigation system was used to accurately locate the stimulation target in this project. Continuous theta short rapid pulse mode (cTBS) was used. CTBS mode consisted of a slave stimulus delivered every 0.2 seconds (5Hz), and each slave stimulus consisted of three bursts of 50Hz. A single stimulus lasts about 40 seconds and totals 600 pulses. Stimulation sessions are from 8 to 10 a.m. daily.
repetitive transcranial magnetic stimulation
The neural navigation system was used to accurately locate the stimulus target.Continuous theta short rapid pulse mode was used. CTBS mode consisted of a slave stimulus delivered every 0.2 seconds (5Hz), and each slave stimulus consisted of three bursts of 50Hz. A single stimulus lasts about 40 seconds and totals 600 pulses.
Control group
Subjects underwent repetitive transcranial magnetic stimulation for five consecutive days from day 2 to day 6 after surgery，but the machine does not turn on.
pseudo repetitive transcranial magnetic stimulation
Participant in control group receive pseudo repetitive transcranial magnetic stimulation
Interventions
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repetitive transcranial magnetic stimulation
The neural navigation system was used to accurately locate the stimulus target.Continuous theta short rapid pulse mode was used. CTBS mode consisted of a slave stimulus delivered every 0.2 seconds (5Hz), and each slave stimulus consisted of three bursts of 50Hz. A single stimulus lasts about 40 seconds and totals 600 pulses.
pseudo repetitive transcranial magnetic stimulation
Participant in control group receive pseudo repetitive transcranial magnetic stimulation
Eligibility Criteria
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Inclusion Criteria
* 45 to 75 years old.
Exclusion Criteria
* failure and decompensation of vital organs
* physical metal implants.
* severe neuropsychiatric disorders.
* less than 9 years of education.
* alcohol abuse.
* drug dependence.
45 Years
75 Years
ALL
No
Sponsors
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The Affiliated Hospital of Xuzhou Medical University
OTHER
Xuzhou Central Hospital
OTHER
Responsible Party
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Principal Investigators
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Yangzi Zhu, Doctor
Role: PRINCIPAL_INVESTIGATOR
Xuzhou Central Hospital
Liwei Wang, Doctor
Role: STUDY_DIRECTOR
Xuzhou Central Hospital
Qi Yang, Doctor
Role: STUDY_DIRECTOR
Beijing Chao Yang Hospital
Daqing Ma
Role: STUDY_CHAIR
Imperial College London, Chelsea and Westminster Hospital
Locations
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Xuzhou Central Hospital
Xuzhou, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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XuzhouCH20221001
Identifier Type: -
Identifier Source: org_study_id
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