Changes of Functional Connectivity After rTMS in Depression
NCT ID: NCT01325831
Last Updated: 2012-02-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
44 participants
INTERVENTIONAL
2009-05-31
2011-06-30
Brief Summary
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Detailed Description
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We scanned fMRIs(to examine functional connectivity)twice for each participant, which were taken 3 days before the first and 3 days after the last rTMS.
All of participants have not reported side effects except mild headahe. There's been no seizure event up to now.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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transcranial magnetic stimluation
repetitive transcranial magnetic stimulation(rTMS)
10-day course of 10 Hz rTMS on left dorsolateral prefrontal cortex of the subjects.
rTMS_sham
Sham repetitive transcranial magnetic stimulation(rTMS)
Sham repetitive transcranial magnetic stimulation(rTMS)
Interventions
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repetitive transcranial magnetic stimulation(rTMS)
10-day course of 10 Hz rTMS on left dorsolateral prefrontal cortex of the subjects.
Sham repetitive transcranial magnetic stimulation(rTMS)
Sham repetitive transcranial magnetic stimulation(rTMS)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Failure of at least 3 different kind of antidepressant
Exclusion Criteria
* Other diagnosis of DMS-IV except nicotine dependence
* History of seizure disorder
19 Years
70 Years
ALL
No
Sponsors
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Yonsei University
OTHER
Responsible Party
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Principal Investigators
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EUN LEE, M.D., Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Yonsei University College of Medicine, Severance Hospital
Locations
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Department of Psychiatry, Severance Hospital
Seoul, , South Korea
Countries
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References
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Kang JI, Lee H, Jhung K, Kim KR, An SK, Yoon KJ, Kim SI, Namkoong K, Lee E. Frontostriatal Connectivity Changes in Major Depressive Disorder After Repetitive Transcranial Magnetic Stimulation: A Randomized Sham-Controlled Study. J Clin Psychiatry. 2016 Sep;77(9):e1137-e1143. doi: 10.4088/JCP.15m10110.
Other Identifiers
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4-2008-0525
Identifier Type: -
Identifier Source: org_study_id
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