The Influence of Food for Special Dietary Use - Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid on Psychophysiological Functions of Subjects Without Meaningful Organic and Cognitive Pathology

NCT ID: NCT05543811

Last Updated: 2023-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-15

Study Completion Date

2023-02-28

Brief Summary

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This is a single-centre, single-blind, two-arms, controlled study to assess the efficacy and safety of food for special dietary use enriched with 5-hydroxytryptophan, L-theanine and Gamma-aminobutyric acid in generally healthy subjects with no cognitive disturbances

Detailed Description

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Conditions

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Cognitive Change Memory; Disturbance, Mild Emotional Regulation Concentration Ability Impaired

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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Product for special dietary use

Spread Enriched With 5-hydroxytryptophan, Theanine and Gamma-aminobutyric Acid will be given to the subjects enrolled to this arm, 20 gram twice daily with breakfast and supper (instead of butter)

Group Type EXPERIMENTAL

Food for special dietary use

Intervention Type DIETARY_SUPPLEMENT

Food for special dietary use (spread) with modified ingredients' content will be included to the diet of 70 patients without significant organic pathology for 14 days receiving standard diet, modified by the inclusion of two portions of the spread, 20 grams each for breakfast and dinner

control

This group will receive standard spread, without theanine, gamma-aminobutyric acid and 5-hydroxytryptophan, twice daily with breakfast and supper with food (instead of butter)

Group Type PLACEBO_COMPARATOR

Food for special dietary use

Intervention Type DIETARY_SUPPLEMENT

Food for special dietary use (spread) with modified ingredients' content will be included to the diet of 70 patients without significant organic pathology for 14 days receiving standard diet, modified by the inclusion of two portions of the spread, 20 grams each for breakfast and dinner

Interventions

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Food for special dietary use

Food for special dietary use (spread) with modified ingredients' content will be included to the diet of 70 patients without significant organic pathology for 14 days receiving standard diet, modified by the inclusion of two portions of the spread, 20 grams each for breakfast and dinner

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* willingness to participate;
* age of 18-50 years

Exclusion Criteria

* pregnancy or breastfeeding;
* significant somatic or psychological disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Group of companies EFKO

UNKNOWN

Sponsor Role collaborator

Russian Science Foundation

OTHER

Sponsor Role collaborator

Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vasily Isakov, Professor

Role: STUDY_CHAIR

Federal Research Center of Nutrition and Biotechnology

Locations

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Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology

Moscow, , Russia

Site Status

Countries

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Russia

Other Identifiers

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19-76-30014/2022-HV

Identifier Type: -

Identifier Source: org_study_id

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