Study of Thyroid Status in Patients With IBD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-31

Study Completion Date

2024-12-31

Brief Summary

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. The aim of the present study is to study thyroid state in patients with IBD

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Detailed Description

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All patients were subjected to history taking and physical examination with emphasis on history of autoimmune disease, extraintestinal manifestations of IBD, neck examination for goiter, symptoms and signs of thyroid dysfunction.

b) Laboratory investigations: Thyroid function test (include T3-T4- TSH)

* ESR - CRP - thyroid antibodies: (Anti TPO -Anti Thyroglobulin)

c)-Imaging:
* Neck U/S on thyroid gland to identify patients with ultrasonographic evidence of autoimmune thyroiditis (diffuse hypoechogenicity or heterogenicity echotexture or both) and to detect thyroid nodularity.

d ) Endoscopic findings regarding diagnosis of IBD confirmed by histopathological examination

Conditions

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Thyroid Disease Irritable Bowel Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Study Groups

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Patients with IBD

All patients were subjected to history taking and physical examination with emphasis on history of autoimmune disease, extraintestinal manifestations of IBD, neck examination for goiter, symptoms and signs of thyroid dysfunction.

b) Laboratory investigations: Thyroid function test (include T3-T4- TSH)

* ESR - CRP - thyroid antibodies: (Anti TPO -Anti Thyroglobulin)

c)-Imaging:
* Neck U/S on thyroid gland to identify patients with ultrasonographic evidence of autoimmune thyroiditis (diffuse hypoechogenicity or heterogenicity echotexture or both) and to detect thyroid nodularity.

d ) Endoscopic findings regarding diagnosis of IBD confirmed by histopathological examination

Thyroid tests

Intervention Type DIAGNOSTIC_TEST

Thyroid function test TSH ,T3,T4 Thyroid antibody test anti TPO,antithyroglobulin

Healty individuals as a control group

All patients were subjected to history taking and physical examination with emphasis on history of autoimmune disease, extraintestinal manifestations of IBD, neck examination for goiter, symptoms and signs of thyroid dysfunction.

b) Laboratory investigations: Thyroid function test (include T3-T4- TSH)

* ESR - CRP - thyroid antibodies: (Anti TPO -Anti Thyroglobulin)

c)-Imaging:
* Neck U/S on thyroid gland to identify patients with ultrasonographic evidence of autoimmune thyroiditis (diffuse hypoechogenicity or heterogenicity echotexture or both) and to detect thyroid nodularity.

Thyroid tests

Intervention Type DIAGNOSTIC_TEST

Thyroid function test TSH ,T3,T4 Thyroid antibody test anti TPO,antithyroglobulin

Interventions

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Thyroid tests

Thyroid function test TSH ,T3,T4 Thyroid antibody test anti TPO,antithyroglobulin

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Thyroid function test and thyroid antibodies

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

* patients with
* Thyroid disease
* Acute or chronic kidney
* Acute or Chronic Liver Disease. Active Lupus -
* Malignancy
* patients taking medications that affect thyroid function as rifampin, amiodarone …..

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes