Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery
NCT ID: NCT05537155
Last Updated: 2025-07-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
NA
INTERVENTIONAL
2022-10-31
2024-03-31
Brief Summary
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Detailed Description
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Clinical use of acupuncture has a long history in China. Buccal acupuncture therapy is a microneedle technique and provides treatment for systemic diseases by acupuncturing specific acupoints in the cheek. Acupuncture is also used for delirium treatment. Studies of older patients who developed delirium in internal medicine wards found that, compared with routine care alone, combining routine care with acupuncture relieved delirious symptoms and severity more efficaciously. However, evidence in this aspect is limited. We suppose that, for older orthopedic patients who developed postoperative delirium, combining buccal acupuncture with routine care will shorten delirium duration and relieve delirium severity.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Buccal acupuncture
Buccal acupuncture will be performed in addition to routine care.
Buccal acupuncture in addition to routine care
Acupuncture will be performed at a depth of 10 mm, with the needle retaining for 20 min, in addition to routine care. Bilateral acupoints include "Tou", "Shangjing", "Jing", "Bei", and "Sanjiao". Unilateral acupoints is related to surgical sites and include "Kuan" in hip joint replacement surgery and "Xi" in knee joint replacement surgery. Patients with agitation will be treated first until agitation is controlled before acupuncture is performed.
Routine care
Routine care will be provided.
Routine care
Routing care includes the following: (1) remove the precipitating cause and treat the primary disease; and (2) supportive care, including reorientation and cognitive stimulation, sleep enhancement, early mobility and exercise, vision and hearing optimization, family engagement and empowerment, and early oral intake and nutrition.
Interventions
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Buccal acupuncture in addition to routine care
Acupuncture will be performed at a depth of 10 mm, with the needle retaining for 20 min, in addition to routine care. Bilateral acupoints include "Tou", "Shangjing", "Jing", "Bei", and "Sanjiao". Unilateral acupoints is related to surgical sites and include "Kuan" in hip joint replacement surgery and "Xi" in knee joint replacement surgery. Patients with agitation will be treated first until agitation is controlled before acupuncture is performed.
Routine care
Routing care includes the following: (1) remove the precipitating cause and treat the primary disease; and (2) supportive care, including reorientation and cognitive stimulation, sleep enhancement, early mobility and exercise, vision and hearing optimization, family engagement and empowerment, and early oral intake and nutrition.
Eligibility Criteria
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Inclusion Criteria
* After knee or hip replacement surgery.
* Diagnosed with delirium in the morning of enrollment.
Exclusion Criteria
* Presence of any contraindications to acupuncture, such as puncture site infections or platelet count ≤20×10\^9/L.
* Preoperative history of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis.
* Inability to communicate due to coma, profound dementia, or language barrier, or inability to cooperate with treatment due to agitation.
* American Society of Anesthesiologists physical status grade ≥V, or estimated survival ≤24 h.
65 Years
90 Years
ALL
No
Sponsors
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Beijing Jishuitan Hospital
OTHER
Peking University First Hospital
OTHER
Responsible Party
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Dong-Xin Wang
Professor and Chairman, Department of Anesthesiology and Critical Care Medicine
Principal Investigators
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Dong-Xin Wang, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Peking University First Hospital
References
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Berian JR, Zhou L, Russell MM, Hornor MA, Cohen ME, Finlayson E, Ko CY, Rosenthal RA, Robinson TN. Postoperative Delirium as a Target for Surgical Quality Improvement. Ann Surg. 2018 Jul;268(1):93-99. doi: 10.1097/SLA.0000000000002436.
Rong X, Ding ZC, Yu HD, Yao SY, Zhou ZK. Risk factors of postoperative delirium in the knee and hip replacement patients: a systematic review and meta-analysis. J Orthop Surg Res. 2021 Jan 22;16(1):76. doi: 10.1186/s13018-020-02127-1.
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Other Identifiers
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2022-220
Identifier Type: -
Identifier Source: org_study_id
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