Predictive Factors of Graft Detachment Following Dmek

NCT ID: NCT05531760

Last Updated: 2022-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

170 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-01

Study Completion Date

2022-06-01

Brief Summary

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The aim of this study was to identify the predictive factors of graft detachment after Descemet Membrane Endothelial Keratoplasty (DMEK) surgery. This retrospective study was conducted on patients aged 18 years, with Fuchs' dystrophy (FECD) or pseudophakic bullous keratopathy (PBK), who were scheduled for DMEK or triple-DMEK (combined phacoemulsification and DMEK surgery). Patients with a history of surgery other than cataract surgery were excluded. The study was conducted between 2014 and 2022 and follow-up was for 3 months. The characteristics of patients with and without graft detachment following surgery were compared using logistic regression.

Detailed Description

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Conditions

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Fuchs' Endothelial Corneal Dystrophy Descemet Membrane Endothelial Keratoplasty Pseudophakic Bullous Keratopathy Graft Detachment

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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DMEK-operated eyes without graft detachment

Eyes operated with DMEK without graft detachment

Descemet Membrane Endothelial Keratoplasty

Intervention Type PROCEDURE

DMEK-operated eyes

DMEK-operated with graft detachment

Eyes operated with DMEK with graft detachment

Descemet Membrane Endothelial Keratoplasty

Intervention Type PROCEDURE

DMEK-operated eyes

Interventions

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Descemet Membrane Endothelial Keratoplasty

DMEK-operated eyes

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients over 18 years of age with DMEK surgery

Exclusion Criteria

* all associated eye surgery other than cataract surgery
* all existing anterior segment anomalies
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Régional Metz-Thionville

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Marc PERONE, MD

Role: PRINCIPAL_INVESTIGATOR

CHR Metz Thionville Hopital de Mercy

Locations

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CHR Metz-Thionville/Hopital de Mercy

Metz, , France

Site Status

Countries

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France

Other Identifiers

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2022-10Obs-CHRMT

Identifier Type: -

Identifier Source: org_study_id

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