Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment

NCT ID: NCT05514951

Last Updated: 2025-03-28

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 888 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-11-15
• Study Completion Date: 2022-12-09

Brief Summary

Iron deficiency is defined by insufficient tissue iron stores and anemia is the ultimate stage of iron deficiency. Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

Detailed Description

Iron deficiency (MD) is defined by insufficient tissue iron stores. Since iron is essential for the synthesis of hemoglobin, when the iron deficiency no longer makes it possible to maintain a sufficient level of erythropoiesis, anemia appears: it is the ultimate stage of iron deficiency.

Anemia is the most common haematological pathology encountered in geriatric practice. Its prevalence, in population generally ambulatory, is between 10 and 15% after the age of 65 and is greater than 20% beyond the age of 85.

Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications heart disease, cognitive decline, frailty, hospitalizations, and impairment of quality of life. About a third of anemias elderly person is attributable to a deficiency in vitamin B9 or B12 or an iron deficiency.

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic such as heart failure, kidney failure chronic or cancer, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

This diagnosis is all the more important because, depending on the chronic pathology, data from the literature have shown that correcting the iron deficiency brings benefits to the patient by reducing the risk of recurrence of anemia, the prescription of erythropoietin and the use of transfusion for patients in oncology, gastroenterology and nephrology

Conditions

Iron-deficiency

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: DIAGNOSTIC
• Blinding Strategy: NONE

Study Groups

Blood sampling

Blood sampling

Group Type: EXPERIMENTAL

Blood sampling

Intervention Type: DIAGNOSTIC_TEST

Blood sampling

Interventions

Blood sampling

Blood sampling

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• Any patient hospitalized in a geriatric unit (short geriatric stay, SSR) or seen on an outpatient basis (hospitalization day, consultation)
• Affiliated patient or beneficiary of a social healthcare system
• Patient having given written consent

Exclusion Criteria

• Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by court order or administration

• Minimum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Vifor Pharma

INDUSTRY

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Chu Angers

Angers, , France

CH de Bayonne

Bayonne, , France

Ch De Calais

Calais, , France

CH Chambéry

Chambéry, , France

CHSF

Corbeil-Essonnes, , France

Ch de Dunkerque

Dunkirk, , France

Hôpital Gériatrique Les Bateliers Chu Lille

Lille, , France

Chu De Nantes, Hôpital Bellier

Nantes, , France

CHU de NICE-hopital CIMIEZ

Nice, , France

Hopital Saint Antoine

Paris, , France

CH de Pau

Pau, , France

CHU de Poitiers

Poitiers, , France

HUS - Hôpitaux Universitaires de Starsbourg

Strasbourg, , France

Hôpital Bretonneau

Tours, , France

Chu Nancy

Vandœuvre-lès-Nancy, , France

HCL

Villeurbanne, , France

Countries

France

References

Fougere B, Puisieux F, Chevalet P, Annweiler C, Michel E, Joly L, Blanc F, Azouzi AE, Desre-Follet V, Cacoub P; CARENFER PA study group*. Prevalence of iron deficiency in patients admitted to a geriatric unit: a multicenter cross-sectional study. BMC Geriatr. 2024 Jan 30;24(1):112. doi: 10.1186/s12877-024-04719-6.

Reference Type: DERIVED

PMID: 38287253 (View on PubMed)

Other Identifiers

2022-A00787-36

Identifier Type: -

Identifier Source: org_study_id