Translational Research Center in Lung Cancer Disparities (TRACER) Project 2

NCT ID: NCT05490251

Last Updated: 2025-12-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

95 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-31

Study Completion Date

2025-08-31

Brief Summary

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The purpose of this study is to examine racial differences in smoking behaviors and stress responses between African American and white male smokers.

Detailed Description

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Cigarette smoking is a leading cause of morbidity and mortality from lung cancer among adults in the US. Stress relief and smoking cessation is the best preventive strategy for reducing lung cancer risk and addressing racial disparities in outcomes. Despite this, racial differences are found among those that make quit attempts. Stress has been found to be related to smoking initiation, maintenance, and relapse. Yet, differences in stress responses have not been examined between African American and white smokers. Therefore, this study will examine racial differences in stress responses and smoking behaviors between African American and white male smokers

Conditions

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Smoking Smoking Behaviors Smoking Cessation Stress Reaction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* African American and white males
* Between the ages of 18-75 years old
* Smoke at least 5 to 10 cigarettes per day

Exclusion Criteria

* Smokers who have a serious cognitive disorder
* Have a personal history of lung cancer
* Personal history of usage of illicit drug and alcohol abuse
* Enrollment in a smoking cessation treatment program during the past 6 months
* Current use of a nicotine replacement therapy
* Have any positive responses on the Mini International Neuropsychiatric Interview (MINI) screener
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Medical University of South Carolina

OTHER

Sponsor Role collaborator

National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

City of Hope Medical Center

OTHER

Sponsor Role collaborator

Virginia Commonwealth University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Winn, MD

Role: PRINCIPAL_INVESTIGATOR

Virginia Commonwealth University

Locations

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University of Southern California

Los Angeles, California, United States

Site Status

Medical University of South Carolina

Charleston, South Carolina, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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00116801

Identifier Type: OTHER

Identifier Source: secondary_id

HM20022956

Identifier Type: OTHER

Identifier Source: secondary_id

MCC-21-18891

Identifier Type: -

Identifier Source: org_study_id

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