Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors

NCT ID: NCT05480644

Last Updated: 2025-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-01

Study Completion Date

2032-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this protocol is to create a repository of blood samples from patients diagnosed with primary and metastatic brain tumors who are being seen in the Department of Radiation Oncology at Duke Cancer Center.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Repository blood samples will be used to study the association of circulating biomarkers with radiation therapy outcomes.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Brain Tumor, Primary Brain Metastases, Adult

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Have a confirmed diagnosis of primary or metastatic brain tumor (histology or imaging as appropriate)

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Duke University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Eugene Vaios, MD MBA

Role: PRINCIPAL_INVESTIGATOR

Duke University Health System (DUHS)

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Duke Cancer Center

Durham, North Carolina, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Kaitlin Bailey, RN OCN

Role: CONTACT

(919) 668-3726

Linda Kaltenbach, PhD

Role: CONTACT

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Kaitlin Bailey, RN

Role: primary

919-668-3726

Linda Kaltenbach, PhD

Role: backup

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Pro00110602

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Biology Studies of Hematologic Cancers
NCT00923442 ENROLLING_BY_INVITATION