Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus

NCT ID: NCT05476692

Last Updated: 2022-07-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-10-01

Study Completion Date

2023-11-01

Brief Summary

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Assess clinical and radiological outcome of the various surgical techniques for treatment of osteochondral lesions of the talus

Detailed Description

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Osteochondritis dissecans (OCD) of the talus is a subchondral bone pathology that presents as an osteochondral lesion of the talar dome with consequent articular cartilage abnormalities. Osteochondral lesions of the talus (OLT) are frequent after acute ankle trauma. The natural history of the OLT remains unclear due to paucity of longitudinal follow-up studies. Various treatment strategies have been described for OLT, including conservative treatment and operative treatment However, the current literature does not allow firm evidence-based recommendations concerning the treatment to be established ; Microfracture is the most common reparative surgery for osteochondral lesions of the talus (OLTs). While shown to be effective in short- to midterm outcomes, the fibrocartilage that microfracture produces is both biomechanically and biologically inferior to that of native hyaline cartilage and is susceptible to possible deterioration over time following repair . Arthroscopic debridement (AD) for the osteochondral lesions of the talar dome (OLT) was widely documented in the nineties with satisfactory results. However, in modern treatment algorithms, its role is not described. A frequently used instrument for assessing outcome after ankle and hindfoot injuries is the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score .

Conditions

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Osteochondral Lesion of Talus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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AOFAS score and VAS

Clinical outcome by the Visual analogue scale (VAS) and the American Orthopaedic Foot and Ankle (AOFAS) score.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age from 15 to 60 years old.
* Traumatic and degenerative etiology.
* without ankle deformity.
* No inflammatory arthritis.
* Absent or corrected ligamentous instability

Exclusion Criteria

* Older than 60 years old and younger than 15 years old.
* Charcot ankle.
* Vascular injury.
Minimum Eligible Age

15 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Mena Magdy Fahmy Dawood

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Mena Magdy

Role: CONTACT

01272640608

Related Links

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https://pubmed.ncbi.nlm.nih.gov/28979588/

Management of Osteochondral Lesions of the Talar Dome

https://pubmed.ncbi.nlm.nih.gov/25606554/

Osteochondritis dissecans of the talus

https://pubmed.ncbi.nlm.nih.gov/33719632/

Long-term Outcomes of Microfracture for Treatment of Osteochondral Lesions of the Talus

Other Identifiers

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OCD of the talus

Identifier Type: -

Identifier Source: org_study_id

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