Serum YKL-40 Level and Platelets Indices Among Patients With Diabetic Erectile Dysfunction

NCT ID: NCT05446493

Last Updated: 2022-07-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-01

Study Completion Date

2022-01-05

Brief Summary

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The aim of this current study is to estimate serum level of YKL-40, serum total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3 months.

Detailed Description

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Conditions

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Erectile Dysfunction Erectile Dysfunction With Diabetes Mellitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Tadalafil group

Each patient will be treated by tadalafil 5mg daily for 3months

Group Type ACTIVE_COMPARATOR

Tadalafil 5mg

Intervention Type DRUG

* Estimate serum level of serum YKL-40, total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3months.
* Penile color Doppler ultrasound examination before and after treatment

control group

Estimation of serum YKL-40, platelet indices and serum total testosterone in healthy individuals in camparing with tadalafil group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Tadalafil 5mg

* Estimate serum level of serum YKL-40, total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3months.
* Penile color Doppler ultrasound examination before and after treatment

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Diabetic patients with ED.

Exclusion Criteria

* Patients with history of pelvic trauma.
* Patients with major pelvic surgical intervention.
* Patients with hypogonadism and hyperprolactinemia.
* Patients with chronic liver disease.
* Patients with cardio vascular system diseases.
* History of chronic intake of central nervous system, anti androgen drugs or other drugs as Tramadol.
* Smokers patients.
* Patients with non-vasculogenic Erectile dysfunction.
Minimum Eligible Age

30 Years

Maximum Eligible Age

70 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Aswan University

OTHER

Sponsor Role lead

Responsible Party

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Mohamed Amer Ahmed Abdellatif

Assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Aswan university

Aswān, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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346/3/19

Identifier Type: -

Identifier Source: org_study_id

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