Study the Safety and Effectiveness of Tadalafil in Men With Problems Getting or Maintaining an Erection When Taken Prior to Desiring an Erection

NCT ID: NCT00547495

Last Updated: 2007-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

343 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-03-31

Study Completion Date

2004-11-30

Brief Summary

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Study to determine how safe and effective tadalafil is for Japanese men taking it when they need to get and keep an erection.

Detailed Description

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Conditions

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Impotence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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1

Placebo tablet

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type DRUG

placebo tablet taken by mouth, as needed, no more than 1 dose per day, for 12 weeks

2

5 mg tadalafil

Group Type ACTIVE_COMPARATOR

tadalafil

Intervention Type DRUG

5 mg tadalafil tablet, by mouth, as needed, no more than 1 dose per day, for 12 weeks

3

10 mg tadalafil

Group Type ACTIVE_COMPARATOR

tadalafil

Intervention Type DRUG

10 mg tadalafil tablet, by mouth, as needed, no more than 1 dose per day, for 12 weeks

4

20 mg tadalafil

Group Type ACTIVE_COMPARATOR

tadalafil

Intervention Type DRUG

20 mg tadalafil tablet, by mouth, as needed, no more than 1 dose per day, for 12 weeks

Interventions

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tadalafil

5 mg tadalafil tablet, by mouth, as needed, no more than 1 dose per day, for 12 weeks

Intervention Type DRUG

placebo

placebo tablet taken by mouth, as needed, no more than 1 dose per day, for 12 weeks

Intervention Type DRUG

tadalafil

10 mg tadalafil tablet, by mouth, as needed, no more than 1 dose per day, for 12 weeks

Intervention Type DRUG

tadalafil

20 mg tadalafil tablet, by mouth, as needed, no more than 1 dose per day, for 12 weeks

Intervention Type DRUG

Other Intervention Names

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LY450190 Cialis IC351 LY450190 Cialis IC351 LY450190 Cialis IC351

Eligibility Criteria

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Inclusion Criteria

* 3 months history of erectile dysfunction (ED)
* Anticipate a monogamous relationship with a female sexual partner
* Be able to make minimum required sexual intercourse attempts
* Abstain from using any other ED treatment

Exclusion Criteria

* Other primary sexual disorders
* History of radical prostatectomy or other pelvic surgery that affected being able to have an erection
* History of penile implant or clinically significant penile deformity.
* Nitrate use
* Certain heart problems
Minimum Eligible Age

20 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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ICOS Corporation

INDUSTRY

Sponsor Role collaborator

Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon- Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Sapporo, Hokkaido, Japan

Site Status

Countries

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Japan

Other Identifiers

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H6D-MC-LVDI

Identifier Type: -

Identifier Source: secondary_id

5139

Identifier Type: -

Identifier Source: org_study_id