Degenerative Cervical Myelopathy Repository

NCT ID: NCT05446259

Last Updated: 2025-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

245 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-13

Study Completion Date

2028-05-31

Brief Summary

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To create a research repository of patients with known degenerative cervical myelopathy (DCM) and a control cohort of subjects who have non-myelopathic spinal disease. This repository will be used to assess functional and/or biological measures that may allow for improved prediction of symptomatic progression and response to treatment in patients with DCM. In addition, this repository will be used to develop a risk assessment scale to accurately predict functional outcomes following operative management of DCM.

Detailed Description

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Conditions

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Cervical Myelopathy

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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DCM group

Subjects diagnosed with degenerative cervical myelopathy.

Standard clinical care procedures and outcome measurements.

Intervention Type OTHER

Standard of care surgical interventions, imaging impressions, laboratory results, and outcome measurements will be collected and analyzed.

Control group

Subjects diagnosed with cervical spinal disease without myelopathic symptoms.

Standard clinical care procedures and outcome measurements.

Intervention Type OTHER

Standard of care surgical interventions, imaging impressions, laboratory results, and outcome measurements will be collected and analyzed.

Interventions

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Standard clinical care procedures and outcome measurements.

Standard of care surgical interventions, imaging impressions, laboratory results, and outcome measurements will be collected and analyzed.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of degenerative cervical myelopathy
* Diagnosis of cervical degenerative disease without myelopathy

Exclusion Criteria

* None outside or diagnostic requirements and age limits.
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Kentucky

OTHER

Sponsor Role lead

Responsible Party

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Francis Farhadi

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Kentucky

Lexington, Kentucky, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Francis Farhadi, MD, PhD

Role: CONTACT

859-562-0247

Jaimie Hixson

Role: CONTACT

859-323-1908

Facility Contacts

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Francis Farhadi, MD, PhD

Role: primary

859-562-0247

Jaimie Hixson, BS

Role: backup

859-323-1908

Other Identifiers

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78340

Identifier Type: -

Identifier Source: org_study_id

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