Study of Microbiological Diversity in Exhaled Air in COPD and Free of COPD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

240 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-26

Study Completion Date

2029-03-31

Brief Summary

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COPD and non-COPD patients will be included in the study after collection of their non-objection. The exhalation will be collected to study the microbiological diversity of human exhalations.

a second collection for the year +1 will be made, at the same time (between October and March).

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Detailed Description

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The subjects will be recruited during a medical visit in the Departments of Pneumology and Occupational and Environmental Pathologies.

After information and inclusion of the subject in the study, a collection of clinical data, the state of health and the smoking status of the subject will be carried out by the clinical study technician.

A collection of the exhalation will also be carried out by the clinical study technician.

Several groups of subjects will be formed according to pathologies (COPD versus non-COPD), age and smoking status

Conditions

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Chronic Obstructive Pulmonary Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Chronic Obstructive Pulmonary Disease (COPD)

Patients with chronic obstructive pulmonary disease will be recruited from the pulmonology or occupational pathology department. They are either active smokers or ex-smokers. They are over 18 years old

collection of human exhalation

Intervention Type OTHER

the collection of the exhalation will be carried out with a non-invasive device manufactured by a Chinese company.

The collection of exhalation consists of the subject inhaling through the nose and exhaling gently through the mouth through a plastic straw for a time set at 5 min in the device

NO-Chronic Obstructive Pulmonary Disease

The no-COPD are controls followed in chi créteil for another pathology. They are between 18 and 30 years old and 45 and 70 years old.

They are either:

* Ex-smoker
* Active smoker
* Non-smoker

collection of human exhalation

Intervention Type OTHER

the collection of the exhalation will be carried out with a non-invasive device manufactured by a Chinese company.

The collection of exhalation consists of the subject inhaling through the nose and exhaling gently through the mouth through a plastic straw for a time set at 5 min in the device

Interventions

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collection of human exhalation

the collection of the exhalation will be carried out with a non-invasive device manufactured by a Chinese company.

The collection of exhalation consists of the subject inhaling through the nose and exhaling gently through the mouth through a plastic straw for a time set at 5 min in the device

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

For COPD:

* Patients with chronic obstructive pulmonary disease
* Age: over 18

For non-COPD

* Absence of chronic obstructive pulmonary disease
* Age: between 18 and 30 years old and between 45 and 70 years old

Exclusion Criteria

* Taking certain medications in the month preceding the sample (antibiotics, systemic corticosteroids, immunosuppressants)
* Person under guardianship or curatorship
* Pregnant or breastfeeding women
* Person unable to express his/her opposition, person deprived of liberty
* Existence of a chronic infectious pulmonary pathology such as (dilation of the bronchi, cystic fibrosis)

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No