Observation of the Natural Course of Age-related Macular Degeneration

NCT ID: NCT05418231

Last Updated: 2022-06-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-31

Study Completion Date

2027-07-31

Brief Summary

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This research will study natural course of dry AMD in Chinese population, screen fundus imaging indicators for patients with Chinese dry AMD, describe the clinical features of Chinese patients with dry AMD, and obtain a biological sample library of dry AMD mainly in China.

Detailed Description

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Conditions

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Dry Age-related Macular Degeneration Macular Degeneration, Dry

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* 50-85 yrs male or female AMD patients
* Dry-AMD patients in either early, intermediate, or intermediate-to-late stage confirmed by fundus examinations.

Exclusion Criteria

* Any eye with disease that would interfere with the retinal examinations
* Research eye with CNV or high myopia
* Surgeries that may interfere with AMD evaluation
* Long-term uses of medications that are associated with retinal or neural toxicities.
* IOP more than 26 mmHg
* Received cataract surgery in 3 months.
* Other conditions: diseases that causes less than 5 years survival; any condition that causes high risk of drop-out, or low compliance, for instance cognition disorder; have been involved in other trial that interfere with the current visit plan; taking other angiogenesis Inhibitors drugs for treating cancer.
* Other conditions not suitable for the current study
Minimum Eligible Age

50 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Xiaodong Sun

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Xiaodong Sun, PHD

Role: PRINCIPAL_INVESTIGATOR

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Locations

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Shanghai General Hospital, Shanghai Jiao Tong University

Shanghai, , China

Site Status

Countries

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China

Central Contacts

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Junran Sun, M.D.

Role: CONTACT

+8613661995933

Other Identifiers

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SXD20220609

Identifier Type: -

Identifier Source: org_study_id

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