Evaluation of the Prognostic Value of Preoperative Quadriceps and Respiratory Muscle Thickness by Ultrasound Measurement in Cardiac and Thoracic Surgery Patients
NCT ID: NCT05412095
Last Updated: 2026-01-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
301 participants
OBSERVATIONAL
2022-05-31
2023-09-26
Brief Summary
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However, it has been shown that the preoperative functional reserves have a significant impact on the patient's risk of developing postoperative complications following major surgery. In addition, there is a strong association between cardiac failure and a well-described decrease in peripheral muscle lean mass (sarcopenia) in patients older than 65 years.
Usually, a nutritional assessment is performed during the pre-anesthesia consultation. This assessment is based on clinical and biological criteria that are not totally predictive of the patient's functional reserve status.
Lean body mass (muscle) is a well-validated marker for the assessment of patients' functional reserves. However, the techniques used to date are complex and require radiation.
This study aims to use ultrasound of muscle groups (respiratory muscles - Quadriceps muscle - Diaphragm) to study the relationship between preoperative muscle mass and postoperative complications in patients over 65 years of age undergoing cardiac or thoracic surgery.
This is a prospective observational study to be conducted at the Dijon University Hospital by the cardiovascular anesthesia-intensive care department. A total of 300 patients will participate in this study, and we have planned to complete the project over a 2-year period. The participating patients (if they do not present any exclusion criteria and are not opposed to inclusion) will be included and undergo a muscle ultrasound in the cardiovascular surgery department or the thoracic and pulmonary surgery department the day before their intervention.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Cardiology patient
Patient requiring cardiac surgery with bypass
Ultrasound of the abdominal wall muscles
the measurements will be performed during inspiration and expiration to take into account variability during the respiratory cycle. The examination is performed bilaterally and comparatively and lasts between 3 and 5 minutes.
Ultrasound quadricipital
The examination is performed bilaterally and comparatively and takes between 3 and 5 minutes.
Ultrasound of the diaphragm
The examination is performed bilaterally and comparatively and takes between 5 and 10 minutes.
Ultrasound of the inter-costal muscles
measurements performed bilaterally on a patient in a half-sitting position at 45° and in spontaneous ventilation
Ultrasound of the inter-costal muscles
In spontaneous ventilation, lying down, arms by the side of the body, palms up, head down
Pneumology patient
Patient requiring lung surgery with resection of at least one lobe
Ultrasound of the abdominal wall muscles
the measurements will be performed during inspiration and expiration to take into account variability during the respiratory cycle. The examination is performed bilaterally and comparatively and lasts between 3 and 5 minutes.
Ultrasound quadricipital
The examination is performed bilaterally and comparatively and takes between 3 and 5 minutes.
Ultrasound of the diaphragm
The examination is performed bilaterally and comparatively and takes between 5 and 10 minutes.
Ultrasound of the inter-costal muscles
measurements performed bilaterally on a patient in a half-sitting position at 45° and in spontaneous ventilation
Ultrasound of the inter-costal muscles
In spontaneous ventilation, lying down, arms by the side of the body, palms up, head down
Interventions
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Ultrasound of the abdominal wall muscles
the measurements will be performed during inspiration and expiration to take into account variability during the respiratory cycle. The examination is performed bilaterally and comparatively and lasts between 3 and 5 minutes.
Ultrasound quadricipital
The examination is performed bilaterally and comparatively and takes between 3 and 5 minutes.
Ultrasound of the diaphragm
The examination is performed bilaterally and comparatively and takes between 5 and 10 minutes.
Ultrasound of the inter-costal muscles
measurements performed bilaterally on a patient in a half-sitting position at 45° and in spontaneous ventilation
Ultrasound of the inter-costal muscles
In spontaneous ventilation, lying down, arms by the side of the body, palms up, head down
Eligibility Criteria
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Inclusion Criteria
* Patients who have not objected to their inclusion in the study
* Any patient requiring elective cardiac surgery, with extracorporeal circulation extracorporeal circulation OR
* Any patient requiring lung surgery with resection of at least one lobe
Exclusion Criteria
* Person who is not affiliated to national health insurance
* Person subject to a measure of legal protection (curatorship, guardianship)
* Pregnant, parturient or breastfeeding women
* Major unable to express consent
* Persons with amputations of the proximal segment of a lower limb
* Persons suffering from a pre-existing neuromuscular pathology, tetra or paraplegia
* Person who must undergo emergency surgery
65 Years
ALL
Yes
Sponsors
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Centre Hospitalier Universitaire Dijon
OTHER
Responsible Party
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Locations
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Chu Dijon Bourgogne
Dijon, , France
Countries
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References
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Berthoud V, Nguyen M, Vinay J, Perrot J, Pages PB, Guinot PG, Bouhemad B. Increase in Diaphragm and Expiratory respiratory muscles thickness is not associated with postoperative pulmonary complications after thoracic surgery: a prospective ultrasound cohort study. Anaesth Crit Care Pain Med. 2025 Nov 12:101683. doi: 10.1016/j.accpm.2025.101683. Online ahead of print.
Other Identifiers
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BERTHOUD 2021
Identifier Type: -
Identifier Source: org_study_id
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