The Effects of Weight Loss on Psoriatic Arthritis

NCT ID: NCT05393141

Last Updated: 2022-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-30

Study Completion Date

2022-10-15

Brief Summary

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Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. This study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach (BETY-Bilişsel Egzersiz Terapi Yöntemi) interventions on symptoms. Accordingly, 45 overweight/obese subjects with PSA aged 20-65 years will divide into "diet", "diet+bety", and "control" groups. Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at the end of the study.

Detailed Description

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Although the underlying cause of PSA is unclear, increased body weight is known to increase the disease symptoms. The present study aims to determine the effects of dietary and Cognitive Exercise Therapy Approach interventions on symptoms.

* Fourt-five overweight/obese subjects with PSA aged 20-65 years will divide into diet (n=15), diet+bety (n=15), and control (n=15) groups.
* Individually diet programs will be applied according to the metabolic, biochemical, and physical activity status of the subjects prepared by a registered dietitian.
* BETY exercise training will be given by a registered physiotherapist.
* The subjects will be followed for 12 weeks.
* Dietary, laboratory and anthropometric records, Short Form Health Survey, DAPSA (Disease Activity in Psoriatic Arthritis), HAQ (Health Assesment Questionnaire) of all subjects will compare at the baseline and at study completion.

Conditions

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Psoriatic Arthritis Obesity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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diet group

weight loss diet intervention for 12 weeks

Group Type EXPERIMENTAL

diet and biopsychosocial exercise intervention

Intervention Type BEHAVIORAL

dietary intervention: biopsychosocial exercise intervention:

diet+bety group

weight loss diet intervention for 12 weeks and exercise-based biopsychosocial approach (Cognitive Exercise Therapy Approach-BETY) intervention for 12 weeks

Group Type EXPERIMENTAL

diet and biopsychosocial exercise intervention

Intervention Type BEHAVIORAL

dietary intervention: biopsychosocial exercise intervention:

control group

no intervention, control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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diet and biopsychosocial exercise intervention

dietary intervention: biopsychosocial exercise intervention:

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* overweight/obese
* diagnosed with PSA

Exclusion Criteria

* pregnancy or lactation
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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Sumeyra Oteles

Clinical Researcher of the Hacettepe University

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sümeyra Öteleş

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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HU-SO-2022

Identifier Type: -

Identifier Source: org_study_id

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