Persona MC vs PS RCT With ROSA

NCT ID: NCT05391828

Last Updated: 2025-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-27

Study Completion Date

2026-12-31

Brief Summary

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A randomized, controlled study comparing two total knee implant devices, Persona medial congruent (MC) vs posterior stabilized (PS). These surgeries will be performed using the ROSA robotic system. Patients will be followed up to 5 years.

Detailed Description

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Conditions

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Total Knee Arthroplasty

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Total Knee Arthroplasty (TKA) performed using a medial congruent articular bearing surface design

Group Type EXPERIMENTAL

Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design

Intervention Type DEVICE

TKA will be performed using the MC Bearing Design. The MC bearing provides medial stability and lateral mobility to facilitate more natural motion.

Total Knee Arthroplasty (TKA) performed using a posterior stabilized bearing design

Group Type ACTIVE_COMPARATOR

Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design

Intervention Type DEVICE

TKA will be performed using the PS Bearing Design. The PS bearings are designed to provide ±1.5 degrees varus/valgus constraint and ± 5.5 degrees internal/external rotation constraint.

Interventions

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Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design

TKA will be performed using the MC Bearing Design. The MC bearing provides medial stability and lateral mobility to facilitate more natural motion.

Intervention Type DEVICE

Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design

TKA will be performed using the PS Bearing Design. The PS bearings are designed to provide ±1.5 degrees varus/valgus constraint and ± 5.5 degrees internal/external rotation constraint.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patients ≥18 years of age
2. Patients scheduled an elective primary TKA for a diagnosis of osteoarthritis or inflammatory arthritis using the ROSA Knee System.
3. Patient is willing to cooperate and follow study protocol and visit schedule
4. Subject has access to a device is capable of pairing to the Apple Watch, supporting application updates and is compatible with the mymobility App.

Exclusion Criteria

1. Patient is pregnant
2. Patient is unable to provide written consent
3. Revision TKA
4. History of prior infection in the affected knee
5. History of prior open surgery with significant hardware in place on the affected knee (i.e. prior distal femur or proximal tibia fracture or osteotomy)
6. Preoperative diagnosis of post-traumatic arthritis, avascular necrosis, or fracture
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vinay Aggarwal, MD

Role: PRINCIPAL_INVESTIGATOR

NYU Langone Health

Locations

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NYU Langone Health

New York, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Vinay Aggarwal, MD

Role: CONTACT

202 250 0679

Daniel Waren

Role: CONTACT

954 559 2251

Facility Contacts

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Vinay Aggarwal

Role: primary

202-250-0679

Other Identifiers

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22-00033

Identifier Type: -

Identifier Source: org_study_id

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