Use of Probiotic Yogurt in Obese Women

NCT ID: NCT05364814

Last Updated: 2022-07-18

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 21 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-02-02
• Study Completion Date: 2022-04-15

Brief Summary

This study aimed to examine the effects of using probiotic yogurt on body components (body weight, height, etc.) and digestive system (distention, gas, etc.) in obesity (obese women), which is an important public health problem all over the world.

Detailed Description

Obesity is an important public health problem worldwide and is associated with non-communicable diseases such as Type 2 Diabetes, hypertension, coronary heart disease, hyperlipidemia, non-alcoholic fatty liver, some neoplasms, and infertility disease.However, it is supported by the literature that nutrition and obesity cause microbial dysbiosis.

In this study, it was aimed to use probiotics and yogurt with the thought that nutrition can manipulate the microbiota.

It was aimed to investigate the effects of probiotic yogurt consumption on anthropometric measurements, metabolic parameters, and gastrointestinal symptoms in obese women (25-45 years old) with the prospective method.

The study was carried out in patients who were diagnosed with obesity by the doctor, consulted the Dietitian, and accepted + signed the voluntary consent form.

Total data and measurements were followed and recorded by the same Dietitian. Compliance with medical nutrition therapy, recording of scales were followed weekly.Patients diagnosed with COVID-19 during the study were excluded from the study.

Conditions

Obesity; Dysbioses

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Obese Group

A single sample group . Anthropometric measurements were taken at the beginning of all patients. Yogurt with probiotic added to medical nutrition therapy was applied for 2 weeks.Anthropometric measurements were taken at the beginning of all patients. Yogurt with probiotic added to medical nutrition therapy was applied for 2 weeks. At the end of each week, food consumption records and scales were applied. During the wash out period, all patients were asked to comply with their diet only. After the wash out period, a different diet was started and the same procedures were repeated.During the wash out period, all patients were asked to comply with their diet only. After the wash out period, a different diet (with the addition of probiotic yogurt) was changed and the same procedures were repeated.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Female patients aged 25-45 years, with a BMI of 27-35 kg/m2 diagnosed as obese by the doctor
• Female patients without a chronic disease
• Female patients between the ages of 25-45 with regular menstrual cycles,
• Female patients between the ages of 25-45 who are not pregnant or lactating
• Female patients who do not use drugs, herbal products, etc. nutritional supplements.

Exclusion Criteria

• Patients with BMI≥ 36 kg/m2
• Patients with diabetes, gastrointestinal diseases, CRF, etc.
• Women in pregnancy and lactation period,
• Male patients
• Weight loss medicine etc. patients with drug use
• Patients who use antibiotics
• Patients using probiotics, propolis, herbal products, etc.
• Patients with menstrual irregularity
• Female patients who have entered the menopause

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Malatya Egitim Ve Arastirma Hastanesi

OTHER_GOV

Sponsor Role: collaborator

Turgut Ozal University

OTHER

Sponsor Role: collaborator

Yuksek Ihtisas University

OTHER

Sponsor Role: lead

Responsible Party

Sevan ÇETİN ÖZBEK

Assistant Proffesor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Sevan ÇETİN ÖZBEK

Role: STUDY_DIRECTOR

Yüksek Ihtisas University

Locations

Malatya Training and Research Hospital

Malatya, , Turkey (Türkiye)

Malatya Training and Research Hospital

Malatya, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

References

Cancello R, Turroni S, Rampelli S, Cattaldo S, Candela M, Cattani L, Mai S, Vietti R, Scacchi M, Brigidi P, Invitti C. Effect of Short-Term Dietary Intervention and Probiotic Mix Supplementation on the Gut Microbiota of Elderly Obese Women. Nutrients. 2019 Dec 10;11(12):3011. doi: 10.3390/nu11123011.

Reference Type: BACKGROUND

PMID: 31835452 (View on PubMed)

Wang ZB, Xin SS, Ding LN, Ding WY, Hou YL, Liu CQ, Zhang XD. The Potential Role of Probiotics in Controlling Overweight/Obesity and Associated Metabolic Parameters in Adults: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019 Apr 15;2019:3862971. doi: 10.1155/2019/3862971. eCollection 2019.

Reference Type: BACKGROUND

PMID: 31118956 (View on PubMed)

Mazloom K, Siddiqi I, Covasa M. Probiotics: How Effective Are They in the Fight against Obesity? Nutrients. 2019 Jan 24;11(2):258. doi: 10.3390/nu11020258.

Reference Type: BACKGROUND

PMID: 30678355 (View on PubMed)

Other Identifiers

YuksekIU02

Identifier Type: -

Identifier Source: org_study_id