Patient Specific Talus Spacer Post Approval Study

NCT ID: NCT05364606

Last Updated: 2024-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-08

Study Completion Date

2029-11-30

Brief Summary

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Humanitarian Device Exemption Approved Patient Specific Talus Spacer Post Approval Study.

Detailed Description

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This is a Humanitarian Device Exemption (HDE) approved device called the Patient Specific Talus Spacer. This is a post approval study to determine the safety and probable benefit of the Patient Specific Talus Spacer in commercial use. The Patient Specific Talus Spacer is a solid polished replica of the patient's bone to allow the patient to regain motion and reduce pain.

Conditions

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Avascular Necrosis of the Talus

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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50 Subjects

50 Subjects Receiving the Patient Specific Talus Spacer.

Patient Specific Talus Spacer

Intervention Type DEVICE

Patient Specific Talus Spacer is a solid polished replica of the patient's bone.

Interventions

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Patient Specific Talus Spacer

Patient Specific Talus Spacer is a solid polished replica of the patient's bone.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subject plans to undergo implantation of the Patient Specific Talus Spacer for avascular necrosis of the ankle joint independent of this research protocol;
2. Avascular necrosis of the ankle joint;
3. Age 21 years old or older;
4. Subject has good general health; and
5. Subject signs a written informed consent form (ICF) prior to the surgical procedure.

Exclusion Criteria

1. Presence of any contraindication identified in the device Instructions for Use;
2. Surgeon determines that the patient is not appropriate for the Talus Spacer procedure based on the device IFU (including the enumerated Warnings and Precautions);
3. Based on the medical opinion of the surgeon, the patient is not appropriate for the Talus Spacer procedure;
4. For female subjects, pregnancy;
5. Active systemic disease, such as AIDS, HIV, or active infection;
6. Active infection or the skin is compromised at the surgical site; and
7. Systemic disease that would affect the subject's welfare;
8. Is a prisoner, incarcerated, or has been coerced to participate in the study that could impact the validity of results;
9. Is currently participating in an investigational therapy (device and/or pharmaceutical) within 30 days prior to entering the study or such treatment is planned during the time course of follow-up.
10. If the Sponsor has notified the site that 30 subjects have been enrolled in the study with a Cobalt Chromium Patient Specific Talus Spacer, and the surgeon believes that a Cobalt Chromium Patient Specific Talus Spacer is the best option for the patient.
11. If the Sponsor has notified the site that 30 subjects have been enrolled in the study with a Titanium (Ti6Al4V) with Titanium Nitride (TiN) coating Patient Specific Talus Spacer, and the surgeon believes that a Titanium (Ti6Al4V) with Titanium Nitride (TiN) coating Patient Specific Talus Spacer is the best option for the patient.
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Paragon 28

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Redwood Orthopaedics

Santa Rosa, California, United States

Site Status RECRUITING

Fort Wayne Orthopedics

Fort Wayne, Indiana, United States

Site Status RECRUITING

Mercy Institute for Foot & Ankle Reconstruction

Baltimore, Maryland, United States

Site Status RECRUITING

Duke Orthopeadics Arringdon

Morrisville, North Carolina, United States

Site Status RECRUITING

Medical University of South Carolina

Charleston, South Carolina, United States

Site Status RECRUITING

UT Physicians Orthopedics - Pearland

Pearland, Texas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jacy Legue

Role: CONTACT

720-399-3400

Caleigh Bates

Role: CONTACT

720-399-3400

Facility Contacts

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Thomas Chang, DPM

Role: primary

707-544-3400

Faith Etherington, PA-C

Role: primary

260-436-8686

Maggie Manchester

Role: primary

Kalynn Purnell

Role: primary

919-681-6035

Josh Morningstar

Role: primary

Jordan Harmon

Role: primary

713-962-9954

Other Identifiers

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AOPSTSPAS

Identifier Type: -

Identifier Source: org_study_id

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