Opioid Reduction Toolkit Reduces Opioids Prescribed and Consumed

NCT ID: NCT05363436

Last Updated: 2024-04-22

Basic Information

• Recruitment Status: SUSPENDED
• Clinical Phase: PHASE4
• Total Enrollment: 159 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-01-01
• Study Completion Date: 2028-12-31

Brief Summary

Investigators studied a baseline population of patients receiving pancreatectomies at their institution and determined how many opioid pills each patient was prescribed and how many they took. Based on this data they created a toolkit to provide to prescribers to give patients a modified number of pills. The amount prescribed and consumed was measured after intervention.

Detailed Description

A single academic surgical department reviewed opioid treatment patterns for patients undergoing common procedures, including open pancreatectomy, and an opioid reduction toolkit using the data collected was created. Providers were educated on the use of the toolkit and it was implemented as a standard of practice. Data were collected on pancreatectomy patients via telephone interview (performed at 2 weeks post-op) and by reviewing the state prescription drug monitoring program. Outcome variables included morphine milliequivalents (MME) of pills prescribed, MME of pills consumed, number of patients aware of proper unused pill disposal, number of patients requesting refills, and pain scores. Categorical and continuous outcomes were compared within and between groups.

Conditions

Opioid Abuse; Opioid Misuse; Pain

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Control

Normal Standard Practices of Prescribing

Group Type: NO_INTERVENTION

No interventions assigned to this group

Intervention

Providers prescribed a base of 15 narcotic pills

Group Type: EXPERIMENTAL

Oxycodone

Intervention Type: DRUG

Providers had to prescribe 15 oxycodone pills to each patient discharge

Interventions

Oxycodone

Providers had to prescribe 15 oxycodone pills to each patient discharge

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Age > 18
• Being scheduled for an outpatient elective pancreatectomy

Exclusion Criteria

• Urgent/emergent status
• Concomitant procedure being performed at time of pancreatectomy

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 99 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Thomas Jefferson University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States

Countries

United States

Other Identifiers

19D.688Panc

Identifier Type: -

Identifier Source: org_study_id