Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free

NCT ID: NCT05362318

Last Updated: 2025-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-07

Study Completion Date

2023-01-28

Brief Summary

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The purpose of the study is to pilot test a multi-modal smoking cessation and relapse prevention intervention with the lung cancer patient population and to obtain preliminary data on its feasibility.

Detailed Description

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Conditions

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Smoking Tobacco Use Lung Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Group 1: Usual Care

Participants will receive brief advice to quit, an offer of enrollment to the Florida Tobacco Quitline, and a 12 week supply of nicotine replacement therapy (nicotine patches and lozenges).

Group Type ACTIVE_COMPARATOR

Nicotine patch and lozenges

Intervention Type DRUG

Participants will receive nicotine patch and lozenges. The regimen will be based on the participant's self-reported smoking rate. At the time of enrollment, a research staff member will determine the proper dose. Participants who smoke \>10 cigarettes/day will receive 8 weeks of 21 mg. patches, 2 weeks of 14 mg. patches, 2 weeks of 7 mg. patches, and 12 weeks of 2 mg. lozenges. Those who smoke \<10 cigarettes/day will receive 8 weeks of 14 mg. patches, 4 weeks of 7 mg patches, and 12 weeks of 2 mg. lozenges

Florida Tobacco Quitline

Intervention Type BEHAVIORAL

Participants will receive an offer of enrollment to the Florida Tobacco Quitline which enables participant to speak with a Quit Coach who will assess nicotine addiction and help create a quit plan.

Group 2: Usual Care + Motivation and Problem Solving + Relapse Prevention

Participants will receive brief advice to quit, an offer of enrollment to the Florida Tobacco Quitline, and a 12 week supply of nicotine replacement therapy (nicotine patches and lozenges), 6 telephone counseling sessions over 6 months, and access to a web based video.

Group Type EXPERIMENTAL

Nicotine patch and lozenges

Intervention Type DRUG

Participants will receive nicotine patch and lozenges. The regimen will be based on the participant's self-reported smoking rate. At the time of enrollment, a research staff member will determine the proper dose. Participants who smoke \>10 cigarettes/day will receive 8 weeks of 21 mg. patches, 2 weeks of 14 mg. patches, 2 weeks of 7 mg. patches, and 12 weeks of 2 mg. lozenges. Those who smoke \<10 cigarettes/day will receive 8 weeks of 14 mg. patches, 4 weeks of 7 mg patches, and 12 weeks of 2 mg. lozenges

Telephone counseling sessions

Intervention Type BEHAVIORAL

Participants will be offered 6 Motivation and Problem Solving (MAPS)-based counseling sessions by phone over a 6-month period.

Access to a web-based video

Intervention Type BEHAVIORAL

Participants will be given web-based access to the relapse prevention video "Surviving Smokefree".

Florida Tobacco Quitline

Intervention Type BEHAVIORAL

Participants will receive an offer of enrollment to the Florida Tobacco Quitline which enables participant to speak with a Quit Coach who will assess nicotine addiction and help create a quit plan.

Interventions

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Nicotine patch and lozenges

Participants will receive nicotine patch and lozenges. The regimen will be based on the participant's self-reported smoking rate. At the time of enrollment, a research staff member will determine the proper dose. Participants who smoke \>10 cigarettes/day will receive 8 weeks of 21 mg. patches, 2 weeks of 14 mg. patches, 2 weeks of 7 mg. patches, and 12 weeks of 2 mg. lozenges. Those who smoke \<10 cigarettes/day will receive 8 weeks of 14 mg. patches, 4 weeks of 7 mg patches, and 12 weeks of 2 mg. lozenges

Intervention Type DRUG

Telephone counseling sessions

Participants will be offered 6 Motivation and Problem Solving (MAPS)-based counseling sessions by phone over a 6-month period.

Intervention Type BEHAVIORAL

Access to a web-based video

Participants will be given web-based access to the relapse prevention video "Surviving Smokefree".

Intervention Type BEHAVIORAL

Florida Tobacco Quitline

Participants will receive an offer of enrollment to the Florida Tobacco Quitline which enables participant to speak with a Quit Coach who will assess nicotine addiction and help create a quit plan.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* Smoked at least 100 cigarettes in lifetime
* Current smoking (defined as self-report of any smoking, even a puff, in the past 30 days)
* Diagnosis of lung cancer
* Able to read and write English
* Not currently enrolled in a smoking cessation program
* Has a working telephone
* Has a valid home address

Exclusion Criteria

* Current use of tobacco cessation medications
* Another household member enrolled in this study
* Contraindication of nicotine patch, unless under the supervision of a physician as advised by project staff
* Moffitt clinical trial participant at time of enrollment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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H. Lee Moffitt Cancer Center and Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vani N Simmons, PhD

Role: PRINCIPAL_INVESTIGATOR

Moffitt Cancer Center

Jennifer I Vidrine, PhD

Role: PRINCIPAL_INVESTIGATOR

Moffitt Cancer Center

Locations

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Moffitt Cancer Center

Tampa, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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MCC-21108

Identifier Type: -

Identifier Source: org_study_id

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