Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking

NCT ID: NCT04409236

Last Updated: 2025-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

PHASE3

Total Enrollment

427 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-19

Study Completion Date

2026-09-11

Brief Summary

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This phase III trial compares the Quit2Heal smoking cessation smartphone application (app) to the QuitGuide app in helping cancer patients quit smoking. Both apps provide tools to cope with urges to smoke, step-by-step guides for quitting smoking, help in planning for quitting and staying tobacco-free, and scientifically-based recommendations for how to select medications that aid in smoking cessation.

Detailed Description

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OUTLINE: Patients are randomized to 1 of 2 arms.

ARM I: Patients receive the Quit2Heal app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

ARM II: Patients receive the QuitGuide app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

After randomization, patients are followed up at 3, 6, and 12 months.

Conditions

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Hematopoietic and Lymphoid System Neoplasm Malignant Solid Neoplasm

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Arm I (Quit2Heal app)

Patients receive the Quit2Heal app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

Group Type EXPERIMENTAL

Quit2Heal

Intervention Type BEHAVIORAL

Use Quit2Heal app

Survey Administration

Intervention Type OTHER

Ancillary studies

Arm II (QuitGuide app)

Patients receive the QuitGuide app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

Group Type ACTIVE_COMPARATOR

QuitGuide

Intervention Type BEHAVIORAL

Use QuitGuide app

Survey Administration

Intervention Type OTHER

Ancillary studies

Interventions

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Quit2Heal

Use Quit2Heal app

Intervention Type BEHAVIORAL

QuitGuide

Use QuitGuide app

Intervention Type BEHAVIORAL

Survey Administration

Ancillary studies

Intervention Type OTHER

Other Intervention Names

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Quit2Heal App Quit2Heal Smartphone App Quit2Heal Smartphone Application QuitGuide App QuitGuide Smartphone App QuitGuide Smartphone Application

Eligibility Criteria

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Inclusion Criteria

* Age 18 or older
* Diagnosed with cancer within the past 24 months or currently receiving or planning to receive cancer treatment in the next 3 months
* Smoked a cigarette (even a puff) in the past 30 days
* Interested in learning skills to quit smoking
* Willing to be randomly assigned to either smartphone application
* Live in the United States and will remain in the United States (US) for the next 12 months
* Have at least daily access to their own smartphone
* Know how to download a smartphone application
* Be willing and able to read English
* Not currently (i.e., within past 30 days) using other smoking cessation interventions
* Have never participated in our prior research trials
* Have never used the National Cancer Institute (NCI)'s QuitGuide app
* Being willing to complete a follow-up survey at 3, 6, and 12 months post-randomization
* Providing email, phone number(s), and mailing address

Exclusion Criteria

* Currently (i.e., within past 30 days) using other smoking cessation interventions
* Has participated in our prior research trials
* Has used the NCI's QuitGuide app
* Not willing to complete a follow-up survey at 3, 6, and 12 months post-randomization
* Not providing email, phone number(s), and mailing address
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

American Cancer Society, Inc.

OTHER

Sponsor Role collaborator

Memorial Sloan Kettering Cancer Center

OTHER

Sponsor Role collaborator

Fred Hutchinson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jonathan Bricker

Role: PRINCIPAL_INVESTIGATOR

Fred Hutch/University of Washington Cancer Consortium

Locations

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Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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NCI-2020-03442

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

10432

Identifier Type: OTHER

Identifier Source: secondary_id

R01CA253975

Identifier Type: NIH

Identifier Source: secondary_id

View Link

RG1007577

Identifier Type: -

Identifier Source: org_study_id

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