Efficacy of Serratus Anterior Plane Block With Dexmedetomidine During Breast Surgery

NCT ID: NCT05361837

Last Updated: 2024-05-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

172 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-10

Study Completion Date

2024-08-25

Brief Summary

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This study aims to compare single level serratus block versus bilevel serratus block with and without dexmedetomidine in cancer patients undergoing modified radical mastectomy for breast cancer regarding pain control and possible side effects.

Detailed Description

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Conditions

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Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Single level serratus anterior plane block

the allocated patients will receive single injection serratus anterior plane block at the level of third rib with local anesthetics only

Group Type ACTIVE_COMPARATOR

Single level serratus anterior plane block

Intervention Type PROCEDURE

Serratus anterior plane block with local anesthetics at the third rib

Single level serratus anterior plane block with dexmedetomidine

the allocated patients will receive single injection serratus anterior plane block at the level of third rib with local anesthetics and dexmedetomidine

Group Type EXPERIMENTAL

Single level serratus anterior plane block with dexmedetomidine

Intervention Type PROCEDURE

Serratus anterior plane block with local anesthetics and dexmedetomidine at the third rib

Bilevel serratus anterior plane block

the allocated patients will receive injection serratus anterior plane block at 2 levels, the level of third rib and the level of the fifth rib with local anesthetics only

Group Type EXPERIMENTAL

Bilevel serratus anterior plane block

Intervention Type PROCEDURE

Serratus anterior plane block with local anesthetics at the third and fifth rib

Bilevel serratus anterior plane block with dexmedetomidine

the allocated patients will receive injection serratus anterior plane block at 2 levels, the level of third rib and the level of the fifth rib with local anesthetics and dexmedetomidine

Group Type EXPERIMENTAL

Bilevel serratus anterior plane block with dexmedetomidine

Intervention Type PROCEDURE

Serratus anterior plane block with local anesthetics and dexmedetomidine at the third and fifth rib

Interventions

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Single level serratus anterior plane block

Serratus anterior plane block with local anesthetics at the third rib

Intervention Type PROCEDURE

Single level serratus anterior plane block with dexmedetomidine

Serratus anterior plane block with local anesthetics and dexmedetomidine at the third rib

Intervention Type PROCEDURE

Bilevel serratus anterior plane block

Serratus anterior plane block with local anesthetics at the third and fifth rib

Intervention Type PROCEDURE

Bilevel serratus anterior plane block with dexmedetomidine

Serratus anterior plane block with local anesthetics and dexmedetomidine at the third and fifth rib

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients scheduled for modified radical mastectomy,
* Age 18-65 years,
* ASA I-II

Exclusion Criteria

* patient refusal,
* coagulation defects,
* abnormal kidney or liver functions,
* local infection at site of injection.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute, Egypt

OTHER

Sponsor Role lead

Responsible Party

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Walaa Youssef Elsabeeny

Assistant professor of Anesthesia and Pain management

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Walaa Y Elsabeeny, MD

Role: PRINCIPAL_INVESTIGATOR

Assistant Professor of Anesthesia and Pain management

Locations

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Walaa Y Elsabeeny

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Walaa Y Elsabeeny, MD

Role: CONTACT

201007798466 ext. +2

Nahla N Shehab, MD

Role: CONTACT

01221682808 ext. +2

Facility Contacts

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Walaa Y Elsabeeny, MD

Role: primary

+201007798466

Other Identifiers

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AP2204-50104

Identifier Type: -

Identifier Source: org_study_id

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