Pecs II Block and PaB Could be an Alternative in Breast Surgery

NCT ID: NCT02865265

Last Updated: 2016-08-12

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 180 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2013-03-31
• Study Completion Date: 2015-12-31

Brief Summary

The association between ultrasound-guided Pecs II block and parasternal block can represent a valid alternative in the management of acute and postoperative pain syndrome after quadrantectomy with or without axillary dissection.

Detailed Description

The combination of Pecs II block and PaB provides good management of postoperative pain and can be considered a viable alternative to common anesthetic procedures performed for breast cancer surgery.

Conditions

Breast Cancer

Study Design

• Study Time Perspective: RETROSPECTIVE

Study Groups

Pecs II and parasternal blocks

Pecs II block was performed at the level of the fourth rib in the fascial plane between the minor pectoral and serratus anterior muscles, and 20 ml of 0.5% levobupivacaine solution were injected.

An ultrasound-guided ipsilateral PaB was performed via two separate injections of 4 ml of 0.375% levobupivacaine at the level of the 2nd and 4th intercostal space underneath the external intercostal membrane between the major pectoral and intercostal muscles close to the surface of the 2nd and 4th rib.

Pecs II and parasternal blocks

Intervention Type: PROCEDURE

Pecs II block was performed at the level of the fourth rib in the fascial plane between the minor pectoral and serratus anterior muscles, and 20 ml of 0.5% levobupivacaine solution were injected.

An ultrasound-guided ipsilateral parasternal block was performed via two separate injections of 4 ml of 0.375% levobupivacaine at the level of the 2nd and 4th intercostal space underneath the external intercostal membrane between the major pectoral and intercostal muscles close to the surface of the 2nd and 4th rib.

Interventions

Pecs II and parasternal blocks

Pecs II block was performed at the level of the fourth rib in the fascial plane between the minor pectoral and serratus anterior muscles, and 20 ml of 0.5% levobupivacaine solution were injected.

An ultrasound-guided ipsilateral parasternal block was performed via two separate injections of 4 ml of 0.375% levobupivacaine at the level of the 2nd and 4th intercostal space underneath the external intercostal membrane between the major pectoral and intercostal muscles close to the surface of the 2nd and 4th rib.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• 18-75 years of age;
• American Society of Anesthesiologists (ASA) physical status I-III,
• patients scheduled for quadrantectomy with or without axillary dissection

Exclusion Criteria

• pregnancy;
• body mass index (BMI) >35;
• allergy to local anesthetics;
• skeletal or muscle abnormalities of the chest wall;
• presence of primary or secondary neurological diseases;
• presence of psychiatric diseases;
• history of chronic pain or neuropathic disorders;
• history of drug abuse;
• state of sepsis;
• infection
• tumors of the skin on the chest;
• primary;
• secondary coagulopathies

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Emiliano Petrucci

OTHER

Sponsor Role: lead

Responsible Party

Emiliano Petrucci

Dr Emiliano Petrucci

Responsibility Role: SPONSOR_INVESTIGATOR

Other Identifiers

0109060/16

Identifier Type: -

Identifier Source: org_study_id