PET-study on the Role of the Reward System in Weight Loss After Bariatric Surgery
NCT ID: NCT05359887
Last Updated: 2024-05-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2022-12-01
2024-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Unsuccessful BS (Total Weight Loss (TWL) < 20%)
Fifteen who had unsuccessful BS (Total Weight Loss (TWL) \< 20%)
standardized liquid mixed meal Nutridrink®
Administration of food in controlled situation
Successful BS (TWL > 25%).
Fifteen who had successful BS (TWL \> 25%).
standardized liquid mixed meal Nutridrink®
Administration of food in controlled situation
Interventions
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standardized liquid mixed meal Nutridrink®
Administration of food in controlled situation
Eligibility Criteria
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Inclusion Criteria
* Adult (over 18y old)
* Mentally capable to understand the consequences of the procedure and make his or her own choice without coercion
* Able to undergo PET and MRI, according to the investigator's assessment
* Native speaking
* Able to participate in follow-up
* Written informed consent
Exclusion Criteria
* The use of drugs that bind to dopamine D2/3 receptors, including various classes of antipsychotics and antidepressants
* History of stroke, brain tumor, Parkinson's Disease or dementia
* History of head trauma with loss of consciousness
* Alcohol or substance abuse in the last 6 months
* Alcohol consumption 24h prior to PET scanning
* Smoking or other forms of nicotine intake 12 hours prior to PET scanning
* Use of anorectic drugs in the last 6 months
* Current pregnancy
* Medication for Diabetes Mellitus
* Claustrophobia
* The presence of implanted metal objects of the type which may concentrate radiofrequency fields or cause tissue damage from twisting in a magnetic field (such as certain implanted devices, shrapnel, ocular metal shavings)
* Patients with a bodyweight \> 200kg will be excluded to ensure the maximum load of the camera bed of the PET-scanner (227 kg) is not exceeded.
18 Years
ALL
No
Sponsors
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University Medical Center Groningen
OTHER
Responsible Party
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Locations
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MCL
Leeuwarden, , Netherlands
Countries
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Central Contacts
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Facility Contacts
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Marlous Emous
Role: primary
Other Identifiers
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UMCG202100632
Identifier Type: -
Identifier Source: org_study_id
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