A Pre-market Study to Evaluate the Performance and Safety of a Skin Preparation Device for Removal of Dry Crusty Skin

NCT ID: NCT05356572

Last Updated: 2023-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-01

Study Completion Date

2023-09-26

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In this clinical one-site investigation the performance and safety of a skin preparation device will be evaluated for removing hyperkeratotic skin prior to further medical treatment. Comfort and pain during skin preparation, as well as performance and safety of device, will be compared to comparators on separate skin areas for every subject.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Keratosis, Actinic Actinic Lesion Solar Keratosis/Sunburn Hyperkeratosis Hyperkeratotic Callus Hyperkeratotic; Lesion Hyperkeratotic Actinic Keratosis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Investigational Skin Preparation Device versus Disposable Dermal Curette

Group Type ACTIVE_COMPARATOR

Investigational Skin Preparation Device

Intervention Type DEVICE

Removal of hyperkeratotic skin with Investigational Skin Preparation Device

UMDNS 13-230 / Biopsy punch (Dermal Curette)

Intervention Type DEVICE

Removal of hyperkeratotic skin with Disposable Dermal Curette

Investigational Skin Preparation Device versus Abrasive Pad for Skin Preparation

Group Type ACTIVE_COMPARATOR

Investigational Skin Preparation Device

Intervention Type DEVICE

Removal of hyperkeratotic skin with Investigational Skin Preparation Device

GMDN 47102 / Electrode Skin Abrasive Pad

Intervention Type DEVICE

Removal of hyperkeratotic skin with Abrasive Pad for Skin Preparation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Investigational Skin Preparation Device

Removal of hyperkeratotic skin with Investigational Skin Preparation Device

Intervention Type DEVICE

GMDN 47102 / Electrode Skin Abrasive Pad

Removal of hyperkeratotic skin with Abrasive Pad for Skin Preparation

Intervention Type DEVICE

UMDNS 13-230 / Biopsy punch (Dermal Curette)

Removal of hyperkeratotic skin with Disposable Dermal Curette

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Attending the clinic for treatment of actinic keratosis using daylight photodynamic therapy
* Age: 18 - 100 years.
* Available for two follow-up visits: two weeks after treatment and 4 months after treatment
* Provision of informed consent i.e., subject must be able to understand and sign the patient Information and Consent Form
* Subject have been informed on the nature, the scope and the relevance of the study

Exclusion Criteria

* Known or suspected allergy/hypersensitivity to phenol formaldehyde
* Wound at the skin site to be treated
* Documented skin disease at the time of enrollment, as judged by the investigator
* Previously enrolled in the present investigation
* Inclusion in other ongoing investigations simultaneously that would preclude the subject from participating in this investigation as judged by the investigator
* Actinic keratosis treatment obtained within last 6 months
* Involvement in the planning and conduct of the clinical investigation (applies to all investigation site staff and third party vendor)
* Any subject that according to Medical Research Act, paragraphs 7-10, is deemed unsuitable for study enrolment.
* Complications that would increase wound risks if investigational product would be used.
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Clinius Ltd

INDUSTRY

Sponsor Role collaborator

Mirka Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Johanna H Hagman, M.D, PhD

Role: PRINCIPAL_INVESTIGATOR

Vaasa Central Hospital, Vaasa, Finland

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Vaasa Central Hospital

Vaasa, , Finland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Finland

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

AMCIREP2204

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Microwave Treatment for Actinic Keratosis
NCT05636800 ACTIVE_NOT_RECRUITING NA