Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-30

Study Completion Date

2025-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) are both common diseases related to metabolic diseases with potential cardiovascular consequences and liver complications respectively. Though studies show OSA may take part in the progression of hepatic steatosis, the independent contribution of OSA on liver fat accumulation is unknown. It is hypothesized that nocturnal intermittent hypoxia from OSA is the main driver of NAFLD in non-obese OSA patients. This study is to assess the effect of OSA on NAFLD in non-obese patients.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Obstructive Sleep Apnea and Non-alcoholic Fatty Liver Disease

NCT03373643

Non-alcoholic Fatty Liver Disease Sleep Apnea, Obstructive

UNKNOWN NA

Obstructive Sleep Apnoea and CPAP Treatment Response in Patients With Non-alcoholic Fatty Liver Disease

NCT02728765

Obstructive Sleep Apnea Non-alcoholic Fatty Liver Disease

COMPLETED NA

The Sleep, Liver Evaluation and Effective Pressure Study

NCT01482065

Non Alcoholic Fatty Liver Disease Obstructive Sleep Apnea

COMPLETED PHASE2

Impact of nCPAP Treatment on Liver Function in Patients With Sleep Apnea Syndrome and Nonalcoholic Steatohepatitis

NCT00152711

Sleep Apnea Syndrome Nonalcoholic Steatohepatitis

UNKNOWN NA

Influence of Craniofacial Restriction on Rebound of Obstructive Sleep Apnea Following Weight Gain

NCT03051815

Observation

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sleep Apnea, Obstructive Fatty Liver

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* aged 18 years or more

Exclusion Criteria

* underlying cause of liver disease
* history of excessive alcoholic consumption (more than 30 g/day for men and 20 g/day for women)
* secondary causes of hepatic steatosis (such as chronic use of systemic corticosteroids)
* positive hepatitis B surface antigen, anti-hepatitis C virus antibody, or histological evidence of other concomitant chronic liver diseases.

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes