Endoscopic Grading of Intestinal Metaplasia

NCT ID: NCT05345314

Last Updated: 2023-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

242 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-01

Study Completion Date

2023-04-24

Brief Summary

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Long-term Helicobacter pylori infection causes premalignant gastric conditions, such as atrophic gastritis and intestinal metaplasia. Image-enhanced endoscopy techniques such as narrow-band imaging (NBI) and magnifying endoscopy improve the diagnosis of gastric intestinal metaplasia (GIM). However, there are no comparative data on the utility of NBI and magnifying endoscopy for diagnosing GIM.

Detailed Description

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This study aims to evaluate the diagnostic performance of NBI and magnifying endoscopy for GIM in a country with high risk of gastric premalignant lesions.

Conditions

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Narrow-band Imaging Magnifying Endoscopy Gastric Intestinal Metaplasia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Narrow-band imaging endoscopy

During endoscopy, gastric mucosal patterns would be examined by magnifying narrow-band imaging.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Gastroscopy can be performed
* Pathological analysis can be performed for analysis of gastric atrophy and intestinal metaplasia

Exclusion Criteria

* Age \< 20 or \> 80 years
* Anemia (serum hemoglobin level \< 10 g/dL)
* Severe systemic disease
* Advanced chronic liver disease
* Use of certain medications, including proton pump inhibitors, H2-receptor antagonists, or antibiotics
* History of H. pylori eradication
* History of gastric surgery
* Recent history of upper gastrointestinal bleeding
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Soonchunhyang University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jun-Hyung Cho

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jun-Hyung Cho, M.D.

Role: PRINCIPAL_INVESTIGATOR

Soonchunhyang University Hospital

Locations

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Digestive Disease Center, Soonchunhyang University Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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SCH-EGD-2022

Identifier Type: -

Identifier Source: org_study_id

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