Evaluative Conditioning: A Brief Cognitive Intervention Aimed to Modify Addiction Behaviour of Alcohol-dependent Patients

NCT ID: NCT05341934

Last Updated: 2022-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-15

Study Completion Date

2019-12-30

Brief Summary

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Evaluative Conditioning: A Brief Cognitive Intervention Aimed to Modify Addiction Behaviour of Alcohol-dependent Patients

Detailed Description

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Conditions

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Cognitive Intervention to Modify Addiction Behaviour of Alcohol-dependent Patients

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Conditionning

Group Type ACTIVE_COMPARATOR

Evaluative Conditionning Task

Intervention Type OTHER

A word will appear in one of the four quadrants on the computer screen. They will have to answer the word as quickly as possible by pressing the space bar. They will also be told that an image will be displayed briefly (400 ms) in the same quadrant by pressing the answer key. This procedure will be repeated for 120 trials: 30 trials with alcohol-related Conditional Stimulus (CS), 30 trials with CS related to non-alcoholic beverages and 60 trials with the CS of filling. The CS referring to alcohol will be the words Beer, Wine …; The CS referring to soft drinks will be the words Coca-Cola, Fanta… and Filling CS referring to vegetables and fruits will be: Apple, Banana…In experimental conditions, alcohol-related CS will be followed by negative Unconditional Stimuli (US) (images from the International Affective Picture System (Lang, Bradley, \& Cuthbert, 1997)), CS referring to soft drinks linked to positive images and CS referring to fruits and vegetables will be linked to neutral US.

Placebo

Group Type PLACEBO_COMPARATOR

Evaluative Conditionning Task

Intervention Type OTHER

A word will appear in one of the four quadrants on the computer screen. They will have to answer the word as quickly as possible by pressing the space bar. They will also be told that an image will be displayed briefly (400 ms) in the same quadrant by pressing the answer key. This procedure will be repeated for 120 trials: 30 trials with alcohol-related Conditional Stimulus (CS), 30 trials with CS related to non-alcoholic beverages and 60 trials with the CS of filling. The CS referring to alcohol will be the words Beer, Wine …; The CS referring to soft drinks will be the words Coca-Cola, Fanta… and Filling CS referring to vegetables and fruits will be: Apple, Banana…In experimental conditions, alcohol-related CS will be followed by negative Unconditional Stimuli (US) (images from the International Affective Picture System (Lang, Bradley, \& Cuthbert, 1997)), CS referring to soft drinks linked to positive images and CS referring to fruits and vegetables will be linked to neutral US.

Interventions

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Evaluative Conditionning Task

A word will appear in one of the four quadrants on the computer screen. They will have to answer the word as quickly as possible by pressing the space bar. They will also be told that an image will be displayed briefly (400 ms) in the same quadrant by pressing the answer key. This procedure will be repeated for 120 trials: 30 trials with alcohol-related Conditional Stimulus (CS), 30 trials with CS related to non-alcoholic beverages and 60 trials with the CS of filling. The CS referring to alcohol will be the words Beer, Wine …; The CS referring to soft drinks will be the words Coca-Cola, Fanta… and Filling CS referring to vegetables and fruits will be: Apple, Banana…In experimental conditions, alcohol-related CS will be followed by negative Unconditional Stimuli (US) (images from the International Affective Picture System (Lang, Bradley, \& Cuthbert, 1997)), CS referring to soft drinks linked to positive images and CS referring to fruits and vegetables will be linked to neutral US.

Intervention Type OTHER

Other Intervention Names

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Implicit Association Task Subliminal Attitude Misattribution Procedure

Eligibility Criteria

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Inclusion Criteria

* Participants in this study will be patients:
* With an alcohol use disorder according to DSM 5
* Follow-up at the Laborit Hospital Center
* Aged between 18 and 70 years with informed consent after receiving written information
* Engaged in a process to reduce alcohol consumption
* With a score of MOCA\> 20
* Whose mother tongue is French
* Patients benefiting from social security or benefiting from it through a third party in accordance with the french law on research involving the human person.

Exclusion Criteria

* \- Patient with less than 6 Heavy Drinking Days in the month
* Patient with Schizophrenia
* Patient with bipolar disorder Type 1
* Patient with Korsakoff syndrome or degenerative neurological disorder
* Patient with hearing impairment, uncorrected visual impairment
* Patient under curatorship or guardianship
* Patient with addiction to another substance other than tobacco
* Patient already enrolled in another interventional study
* Pregnant or nursing woman
* Patient with difficulties of expression or comprehension in French
* Patients in emergency situations or unable to give their consent.

Output Criteria:

* Patient who has manifested verbally or in writing, the desire to leave the study in progress.
* Patient who will be hospitalized during the study for a problem related to his addiction.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Henri Laborit

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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JAAFARI NEMATOLLAH, PROFESSOR

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Henri Laborit

Locations

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Centre Hospitalier Henri Laborit

Poitiers, , France

Site Status

Countries

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France

Other Identifiers

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2017-A02120-53

Identifier Type: -

Identifier Source: org_study_id

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