Trial Outcomes & Findings for Impact of a Family History of Hypertension and Physical Activity on Left Ventricular Mass (NCT NCT05334355)
NCT ID: NCT05334355
Last Updated: 2025-02-24
Results Overview
Muscle mass in grams of the left ventricle of the heart as estimated by ultrasound.
Recruitment status
COMPLETED
Target enrollment
74 participants
Primary outcome timeframe
Day 2
Results posted on
2025-02-24
Participant Flow
Participant milestones
| Measure |
Positive Family History of Hypertension
Young normotensive generally healthy adult with one or more biological parents with diagnosed hypertension.
Family history of hypertension: Presence or absence of a family history of hypertension in a cross sectional study design.
|
Negative Family History of Hypertension
Young normotensive generally healthy adult with no biological parent with diagnosed hypertension.
|
|---|---|---|
|
Overall Study
STARTED
|
37
|
37
|
|
Overall Study
COMPLETED
|
29
|
32
|
|
Overall Study
NOT COMPLETED
|
8
|
5
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Impact of a Family History of Hypertension and Physical Activity on Left Ventricular Mass
Baseline characteristics by cohort
| Measure |
Positive Family History of Hypertension
n=29 Participants
Young normotensive generally healthy adult with one or more biological parents with diagnosed hypertension.
Family history of hypertension: Presence or absence of a family history of hypertension in a cross sectional study design.
|
Negative Family History of Hypertension
n=32 Participants
Young normotensive generally healthy adult with no biological parent with diagnosed hypertension.
|
Total
n=61 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
29 Participants
n=5 Participants
|
32 Participants
n=7 Participants
|
61 Participants
n=5 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Age, Continuous
|
23.44827586 years
STANDARD_DEVIATION 2.384266987 • n=5 Participants
|
22.6875 years
STANDARD_DEVIATION 2.966887149 • n=7 Participants
|
23.04918033 years
STANDARD_DEVIATION 2.7106 • n=5 Participants
|
|
Sex: Female, Male
Female
|
18 Participants
n=5 Participants
|
19 Participants
n=7 Participants
|
37 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
11 Participants
n=5 Participants
|
13 Participants
n=7 Participants
|
24 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
4 Participants
n=5 Participants
|
8 Participants
n=7 Participants
|
12 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
25 Participants
n=5 Participants
|
24 Participants
n=7 Participants
|
49 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
29 Participants
n=5 Participants
|
32 Participants
n=7 Participants
|
61 Participants
n=5 Participants
|
|
Left Ventricular Mass/Body Surface Area
|
88.35017813 grams/meter squared
STANDARD_DEVIATION 17.30587475 • n=5 Participants
|
73.51184729 grams/meter squared
STANDARD_DEVIATION 17.74896472 • n=7 Participants
|
80.56613572 grams/meter squared
STANDARD_DEVIATION 18.9302 • n=5 Participants
|
PRIMARY outcome
Timeframe: Day 2Muscle mass in grams of the left ventricle of the heart as estimated by ultrasound.
Outcome measures
| Measure |
Positive Family History of Hypertension
n=29 Participants
Young normotensive generally healthy adult with one or more biological parents with diagnosed hypertension.
Family history of hypertension: Presence or absence of a family history of hypertension in a cross sectional study design.
|
Negative Family History of Hypertension
n=32 Participants
Young normotensive generally healthy adult with no biological parent with diagnosed hypertension.
|
|---|---|---|
|
Left Ventricular Mass
|
155.1680523 gram
Standard Deviation 42.6141251
|
129.5013331 gram
Standard Deviation 41.76454204
|
Adverse Events
Positive Family History of Hypertension
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Negative Family History of Hypertension
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. Evan Matthews, Associate Professor
Montclair State University
Phone: 9736553948
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place