Surgery or Chemoradiotherapy for Cervical Esophageal Cancer
NCT ID: NCT05327517
Last Updated: 2022-04-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
192 participants
INTERVENTIONAL
2022-04-10
2028-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Surgery
Patients receive esophagectomy or neoadjuvant therapy plus esophagectomy
Esophagectomy
Patients receive esophagectomy or definitive chemoradiotherapy according to patient preference
Definitive chemoradiotherapy
Patients receive definitive chemoradiotherapy
Esophagectomy
Patients receive esophagectomy or definitive chemoradiotherapy according to patient preference
Interventions
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Esophagectomy
Patients receive esophagectomy or definitive chemoradiotherapy according to patient preference
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Cervical esophageal cancers spreads upwards to involve the hypopharynx and downwards to involve the thoracic esophagus can also be included;
* Aged 18-75 years;
* Without any contraindication of operation;
* Hemoglobin \>=90 g/L; Leukocytes \>=4.0x10\^9/L; Absolute neutrophil count \>=1.5x10\^9/L; Platelet \>=100x10\^9/L;Total bilirubin \<=1.5 ULN; ALT \<=2.5 ULN; AST \<=2.5 ULN; Serum creatinine \<=1.5 ULN or creatinine clearance rate \>=50 mL/min (Cocheroft-Gault);INR \<=1.5 ULN; APTT \<=1.5 ULN;
* Without other malignancies;
* Expected R0 resection;
* ECOG PS 0-1;
* Volunteered to participate in the study, signed the informed consent form.
Exclusion Criteria
* With mental diseases;
* With hemorrhagic disease;
* Inoperable patients;
* Pregnant or lactating women;
* Has a history of allergy to paclitaxel or cisplatin
18 Years
75 Years
ALL
No
Sponsors
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Cancer Institute and Hospital, Chinese Academy of Medical Sciences
OTHER
Responsible Party
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Principal Investigators
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Jie He, MD
Role: STUDY_DIRECTOR
Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Yin Li, MD
Role: PRINCIPAL_INVESTIGATOR
Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Locations
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Cancer Hospital Chinese Academy of Medical Sciences
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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NCC3281
Identifier Type: -
Identifier Source: org_study_id
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