Leveraging Technology to Achieve Equity for Men With Prostate Cancer on Androgen Deprivation Therapy

NCT ID: NCT05324098

Last Updated: 2024-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

47 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-08

Study Completion Date

2023-07-31

Brief Summary

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This clinical trial studies a digital platform, the supportive therapy in androgen deprivation (STAND-T), in achieving equity for men undergoing treatment with androgen deprivation therapy for prostate cancer. STAND-T is a digital platform that provides prostate health information, evidence-based materials and resources. STAND-T may help improve health, address symptoms, and promote equity in men with prostate cancer.

Detailed Description

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PRIMARY OBJECTIVE:

I. To assess study feasibility of the STAND-T program at the Helen Diller Family Comprehensive Cancer Center (HDFCCC) and Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG) genitourinary (GU) medical, surgical, and radiation oncology practices.

SECONDARY OBJECTIVE:

I. To measure preliminary estimates of acceptability and usage of a digital platform, STAND-T.

EXPLORATORY OBJECTIVE:

I. To describe diet (e.g., fruit and vegetable intake), lifestyle (e.g., moderate to vigorous exercise, smoking status), clinical (symptoms e.g., fatigue), and health related quality of life (QoL) outcomes (e.g., sleep disturbance), physiologic measures (body mass index, BMI) at baseline and change in these metrics from baseline to 3 months post-intervention.

OUTLINE:

Patients review educational material and resources via online STAND-T platform. Patients also receive interactive text messages for 3 months.

After completion of study, patients are followed up at 3 months.

Conditions

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Prostate Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Health services research (STAND-T, text messages)

Patients review educational material and resources via online STAND-T platform. Patients also receive interactive text messages for 3 months.

Group Type EXPERIMENTAL

STAND-T platform

Intervention Type OTHER

Internet-based intervention comprised of evidence-based, patient materials and resources

Survey Administration

Intervention Type OTHER

Satisfaction and follow-up surveys will be administered to participants

Text Messages

Intervention Type OTHER

Participants will receive periodic text messages

Interventions

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STAND-T platform

Internet-based intervention comprised of evidence-based, patient materials and resources

Intervention Type OTHER

Survey Administration

Satisfaction and follow-up surveys will be administered to participants

Intervention Type OTHER

Text Messages

Participants will receive periodic text messages

Intervention Type OTHER

Other Intervention Names

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STAND-T Short Message Service (SMS) Text

Eligibility Criteria

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Inclusion Criteria

* Age \>18 years
* Ability to understand study procedures and to comply with them for the entire length of the study
* Ability of individual or legal guardian/representative to understand an informed consent document and the willingness to sign it
* Adenocarcinoma of the prostate
* Current or planned anti-androgen therapy (ADT) (oral or injection) with gonadotropin-releasing hormone (GnRH) antagonist or luteinizing hormone releasing hormone (LHRH) agonist
* Life expectancy duration of 6 months or longer from date of study consent
* Prior and concurrent radiation is allowed
* Treatment with concurrent androgen signaling inhibitors is allowed
* \< 75 minutes/week of vigorous aerobic exercise based on Godin survey or \< 2 days per week of vigorous activity

Exclusion Criteria

* Contraindication to any study-related procedure or assessment
* Planned surgery/chemotherapy/immunotherapy/parp inhibitor treatment during the study period
* Prior and concurrent investigational therapies
* Unable to read/speak English
* Unable to access the Internet
* Has seen an exercise counselor in the past 6 months for prostate or cardiovascular health
* Has seen a dietary counselor in the past 6 months for prostate or cardiovascular health
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Myovant Sciences GmbH

INDUSTRY

Sponsor Role collaborator

University of California, San Francisco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stacey Kenfield, DSc

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

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Zuckerberg San Francisco General Hospital

San Francisco, California, United States

Site Status

University of California, San Francisco

San Francisco, California, United States

Site Status

Countries

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United States

References

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Wang EY, Borno HT, Washington Iii SL, Friedlander T, Zhang S, Trejo E, Van Blarigan EL, Chan JM, Shariff-Marco S, Beatty AL, Kenfield SA. Engaging Men of Diverse Racial and Ethnic Groups With Advanced Prostate Cancer in the Design of an mHealth Diet and Exercise Intervention: Focus Group Study. JMIR Cancer. 2023 Jun 1;9:e45432. doi: 10.2196/45432.

Reference Type DERIVED
PMID: 37261885 (View on PubMed)

Other Identifiers

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NCI-2022-02225

Identifier Type: REGISTRY

Identifier Source: secondary_id

215514

Identifier Type: -

Identifier Source: org_study_id

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