Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia

NCT ID: NCT05314582

Last Updated: 2023-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-10

Study Completion Date

2023-01-10

Brief Summary

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Patients who were using anticoagulant or antiaggregant medications for any reason and underwent transurethral resection of bladder tumor (TUR-BT) or transurethral resection of the prostate (TURP) or open prostatectomy (OP) due to BPH will be compared with those who were not using anticoagulant or antiplatelet medication. The rates of postoperative clot retention, presence of hematuria, reoperation due to hematuria, blood transfusion and re-admissions due to hematuria in the first postoperative month will be compared.

Detailed Description

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Conditions

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Hematuria Retention, Urinary Operative Bleeding Blood Transfusion Complication

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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TURP patients using anticoagulant/antiaggregant medication

Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent endoscopic prostatectomy (TURP).

No interventions assigned to this group

TURP patients not using anticoagulant/antiaggregant medication

Patients with no history of anticoagulant/antiaggregant medication and underwent endoscopic prostatectomy (TURP).

No interventions assigned to this group

TUR-BT patients using anticoagulant/antiaggregant medication

Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent endoscopic bladder tumor resection (TUR-BT).

No interventions assigned to this group

TUR-BT patients not using anticoagulant/antiaggregant medication

Patients with no history of anticoagulant/antiaggregant medication and underwent endoscopic bladder tumor resection (TUR-BT).

No interventions assigned to this group

Open prostatectomy patients using anticoagulant/antiaggregant medication

Patients who used anticoagulant/antiaggregant medication for any reason (eg: coronary artery disease, atrial fibrillation, cerebrovascular disease) before surgery and underwent open prostatectomy (OP).

No interventions assigned to this group

Open prostatectomy patients not using anticoagulant/antiaggregant medication

Patients with no history of anticoagulant/antiaggregant medication and underwent open prostatectomy (OP).

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing complete endoscopic transurethral tumor resection (TUR-BT) for bladder cancer
* Patients undergoing TURP due to benign prostatic hyperplasia
* Patients undergoing open prostatectomy due to benign prostatic hyperplasia

Exclusion Criteria

* Patients who underwent incomplete transurethral tumor resection for bladder cancer
* Patient who underwent TUR biopsy for restaging with no obvious macroscopic tumoral lesion
* Patients who underwent cystectomy for bladder cancer
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bezmialem Vakif University

OTHER

Sponsor Role lead

Responsible Party

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Abdullah İlktaç

Pincipal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Abdullah Ilktac, MD

Role: STUDY_CHAIR

Bezmialem Vakif University, Faculty of Medicine, Department of Urology

Locations

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Bezmialem Vakif University

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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196083

Identifier Type: -

Identifier Source: org_study_id

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