Neural Mobilization for Reduction of Spasticity in Stroke

NCT ID: NCT05314465

Last Updated: 2022-08-17

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 7 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-11-22
• Study Completion Date: 2022-03-15

Brief Summary

Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and improving upper limb strength. This study aimed to explore and understand the effectiveness of neural mobilization on reduction of spasticity and improving upper limb strength in individuals with stroke. This is mixed method approach of embedded design, multicentric study recruited 7 individuals with stroke as no new themes or codes were emerging (data saturated). Median nerve mobilization was given 20 oscillations per minute for 3 times & repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks. Outcome measures were Modified Ashworth Scale (MAS), Brunnstrom's grading of hand recovery and Hydraulic hand dynamometer(HHD) for grip and pinch strength. Pre and post outcomes data were collected at baseline and 4weeks after intervention and in depth face to face structured interviews was conducted after 4weeks of intervention to explore the effectiveness of median nerve mobilization on reduction of spasticity and the improvement of upper limb strength.

Detailed Description

Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and improving upper limb strength. This study aimed to explore and understand the effectiveness of neural mobilization on reduction of spasticity and improving upper limb strength in individuals with stroke. This is mixed method approach of embedded design, multicentric study recruited 7 individuals with stroke as no new themes or codes were emerging (data saturated). Median nerve mobilization was given 20 oscillations per minute for 3 times & repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks. Primary outcome measure was Modified Ashworth Scale (MAS) to assess elbow and wrist flexors spasticity and secondary outcome measures were Brunnstrom's stages for hand recovery and Hydraulic hand dynamometer(HHD) to measure grip and pinch strength. Pre and post outcomes data were collected at baseline and 4weeks after intervention and in depth face to face structured interviews was conducted after 4weeks of intervention to explore the effectiveness of median nerve mobilization on reduction of spasticity and the improvement of upper limb strength.

Conditions

Stroke

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Median nerve mobilization

Experimental arm given Median nerve mobilization for 12mins 3sets for 3mins each with 1 minute interval in between for 5times a week for 4weeks

Group Type: EXPERIMENTAL

Median nerve mobilization

Intervention Type: OTHER

Median nerve mobilization was given 20 oscillations per minute for 3 times \& repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks.

Interventions

Median nerve mobilization

Median nerve mobilization was given 20 oscillations per minute for 3 times \& repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. Participants with subacute and chronic stroke (1month and above) having upper limb spasticity.

2. Participants with haemorrhagic and ischemic stroke.

3. Participants who tolerate the supine position.

4. Participants who are oriented and alert.

5. Both males and females.

6. Participants older than 18 years.

Exclusion Criteria

1. Participants with a score greater than 3 on The Modified Ashworth Scale.

2. Participants with affected speech.

3. Participants with upper limb deformity.

4. Participants experiencing dizziness.

5. Any increase in the dosage of anti-spastic medications during the intervention period.

6. General health problems or pathologies that affect the nervous system like uncontrolled diabetes, hypertension and recent surgeries.

7. Recent onset of worsening neurological signs.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Asir John Samuel

OTHER

Sponsor Role: lead

Responsible Party

Asir John Samuel

Professor

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Rittu Sharma, (MPT)

Role: PRINCIPAL_INVESTIGATOR

Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation

Asir John Samuel, Ph.D

Role: STUDY_CHAIR

Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation

Akanksha Saxena, (Ph.D)

Role: STUDY_DIRECTOR

Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation

Locations

Maharishi Markandeshwar Institute of Physiotherapy & Rehabilitation

Ambāla, Haryana, India

Healing Hands Physiotherapy & Rehabilitation

Hisar, Haryana, India

Bedi Hospital

Kaithal, Haryana, India

Countries

India

Other Identifiers

U1111-1276-6515

Identifier Type: OTHER

Identifier Source: secondary_id

MMDU/IEC/1935

Identifier Type: -

Identifier Source: org_study_id