Secondary Prevention With the Lifestyle Tool

NCT ID: NCT05309876

Last Updated: 2025-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

11000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-06

Study Completion Date

2028-12-31

Brief Summary

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In this study participants will be randomized to use a digital lifestyle tool over three years or to a control group without access to the tool. The investigators will prospectively follow the incidence of major cardiovascular events in patients who have previously suffered from a myocardial infarction in those using the tool regularly and those in the control group.

Detailed Description

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Cardiovascular disease (CVD) remains a leading cause of death in most European countries, and new strategies for prevention are urgently needed.

Previous studies on primary and secondary prevention have shown that lifestyle interventions can affect risk factors for CVD and reduce cardiovascular morbidity and mortality. Many prevention programmes are, however, time-limited and fail to provide continuous support. They also require substantial costs and healthcare resources. Furthermore, accessibility to primary and secondary cardiac prevention programmes is highly variable, as is long-term adherence to lifestyle advice.

In light of this, international associations have emphasized the need for innovative, scalable and cost-effective lifestyle interventions that could be integrated into pre-existing healthcare structures. Digital tools have large potential for clinical utility, but there are several important knowledge gaps. First, data on long-term efficacy is scarce. Second, most studies to date have included only small number of individuals, and there is a need for large randomized controlled studies. Third, cost-effectiveness remains to be demonstrated.

The objective or this study is to evaluate a new web-based tool, developed at the University Gothenburg, Sweden, that aims to support patient autonomy and motivation to make sustainable lifestyle changes.

In individuals who have previously suffered from a myocardial infarction the investigators will test the hypothesis that those who access to the tool have lower incidence of further major cardiovascular events (MACE) compared with control individuals.

The study is an investigator-initiated single-center study conducted over three years.

The tool is web-based and used via a computer or mobile phone. It is used at each individual's preferred pace but participants are recommended to login at least every other week. Every round the participants choose a themes (out of appr. 80 possible covering e.g. food, exercise, stress, self-reflection aspects), which takes appr. 15-30 minutes to complete. Participants then reflect on the content and how it could be implemented in daily life. When returning for next round participants are asked to reflect on any changes done since last time.

Conditions

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Cardiovascular Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants get access to the tool or get assigned to a control group without access
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Usage of tool

Participants get access to the tool and use it regularly

Group Type EXPERIMENTAL

Lifestyle tool

Intervention Type BEHAVIORAL

Regular use of the digital Lifestyle tool

Controls on usual care

Participants who get randomized to control cannot access the tool. Development of cardiovascular disease is followed via clinical registries.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Lifestyle tool

Regular use of the digital Lifestyle tool

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* age 35 to 80 years
* myocardial infarction within one year prior to enrolment
* access to computer or mobile phone.

Exclusion Criteria

* conditions or treatments that in the judgement of the Investigator could affect the study evaluation
Minimum Eligible Age

35 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Region Skane

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anders Rosengren, Professor

Role: PRINCIPAL_INVESTIGATOR

Göteborg University

Locations

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Skane University Hospital

Malmo, , Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Birgitta Abrahamsson

Role: CONTACT

0705316704

Facility Contacts

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Anders Rosengren

Role: primary

Other Identifiers

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Lifestyle3

Identifier Type: -

Identifier Source: org_study_id

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