Plethysmography Curve Variability Depending on the Breath Cycle

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-10

Study Completion Date

2022-06-30

Brief Summary

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The aim of the study is to analyze the variability of plethysmography curve depending on the breath cycle (respiratory rate and tidal volume).

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Detailed Description

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The plethysmography curve measured by finger sensors using pulse oximetry shows the changes in blood volume at the measured site. The presence of respiratory information within the pulse oximeter signal is a well-documented phenomenon. However, previous studies have mainly focused on extracting the respiratory rate from the plethysmography curve. The aim of this study is to analyze the variability of plethysmography curve as a function of both respiratory rate and tidal volume. Furthermore, the aim is to analyze the possibilities of apneic pause detection from the plethysmography curve.

Conditions

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Apnea Circulatory; Change Respiration

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

All participants go through all assigned interventions in one study arm.

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Measurement of plethysmography curve

Calm measurement of plethysmography curve using pulse oximetry with simultaneous monitoring of the breath cycle. In this experimental arm, participants will vary their breath cycle (different respiratory rates and different tidal volumes).

Group Type EXPERIMENTAL

Respiratory rate

Intervention Type OTHER

The participant alternates respiratory rates of 30, 15 and 7.5 breaths/min. Breathe each frequency for 2 minutes with a one-minute break.

Tidal volume

Intervention Type OTHER

The participant alternates tidal volumes of approx. 2, 1 and 0.5 litres. Breathe each tidal volume for 2 minutes with a one-minute break.

Apnea

Intervention Type OTHER

The participant simulates three apneic pauses lasting 1 minute with a two-minute break.

Interventions

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Respiratory rate

The participant alternates respiratory rates of 30, 15 and 7.5 breaths/min. Breathe each frequency for 2 minutes with a one-minute break.

Intervention Type OTHER

Tidal volume

The participant alternates tidal volumes of approx. 2, 1 and 0.5 litres. Breathe each tidal volume for 2 minutes with a one-minute break.

Intervention Type OTHER

Apnea

The participant simulates three apneic pauses lasting 1 minute with a two-minute break.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy volunteers/students from the Czech Technical University in Prague

Exclusion Criteria

* any acute illness
* pregnancy
* severe cardiovascular conditions
* severe asthma or other severe respiratory conditions
* diabetes
* hypotension or hypertension

Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes