Breast MRI in Evaluation of Pathologic Response in Patients With Breast Cancer With Neoadjuvent Chemotherapy

NCT ID: NCT05301790

Last Updated: 2022-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-05-31

Study Completion Date

2024-12-31

Brief Summary

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evaluation of pathological response in breast mass by use of breast MRI in patients receiving neoadjuvent chemotherapy via comparison with pathological results

Detailed Description

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evaluation of pathological response in locally advanced breast masses by use of breast MRI in patients receiving neoadjuvent chemotherapy via comparison with pathological results

Conditions

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Role of MRI in Evaluation of Breast Cancer

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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MRI

use of MRI modality of imaging in evaluation of pathologic response in patients with breast cancer

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* all women referred to the radiology department for breast MRI examination either for screening, evaluation of suspicious lesions onsono-mammography \\

* Patients with locally advanced breast cancer
* Patients with early stage breast cancer and chemo-responsive tumour markers (i.e. triple negative, Her2+), who will benefit from downsizing for breast conserving surgery (BCS)
* Absolute or Relative contraindications to surgery (advanced age/multiple medical comorbidities) in the setting of estrogen receptor positive tumours (for consideration of neoadjuvant endocrine therapy)3
* Patients must be elder than 18 years old.
* patients with accepted renal function

Exclusion Criteria

* Patients with metastatic breast cancer.
* Patient with breast mass more than 5 cm .
* Patients with fungating breast mass .
* Patients with stage IV \[tumor spread to chest wall and to skin \].
* pregnant women especially in 1th trimester.
* Patient with presence of any paramagnetic substance as pacemakers.
* severely ill patients .
* patients with claustrophobia.
* arrhythmic patients
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Doaa Maher Ebied Maher

resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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lamiaa mohamed refaat, assisstant professor

Role: STUDY_DIRECTOR

assiut university -south egypt cancer institute

omar mostafa, lecturer

Role: STUDY_DIRECTOR

assiut university-south egypt cancer institute

Central Contacts

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Doaa Maher, resident

Role: CONTACT

01050147500

hasan megally, professor

Role: CONTACT

01006209584

Other Identifiers

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MRI in breast cancer

Identifier Type: -

Identifier Source: org_study_id

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