Multidisciplinary Intervention With Cognitive Remediation Therapy for Obese Adults

NCT ID: NCT05295745

Last Updated: 2022-03-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-08

Study Completion Date

2023-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aims to describe the research procedures and treatment of a multidisciplinary intervention with cognitive remediation therapy for adults with obesity in a Randomized Controlled Trial. The changes will be measured before and after the intervention and three months follow-up. To evaluate them, psychometric, psychological, physiological, and physical activity tests will be taken.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A randomized controlled clinical trial will be carried out, implementing a multidisciplinary intervention with cognitive remediation therapy on obese adults from Ciudad Juárez, Chihuahua, México. The efficacy of this therapy has been proved in several countries except México.

A randomized controlled trial (RCT) will be executed with both an experimental group and a control group, with repeated measures taken before and after intervention and follow ups of three months. The study will be simple blind and randomization technique will be use to one assign to one of the two conditions. The experimental group will first receive the intervention and once finalized, it will be applied to the control group.

The investigator's hypothesis suggests that an intervention of cognitive remediation therapy implemented simultaneously with nutritional education and physical activity improvement in body composition such a body mass index (BMI), waist ratio, body fat, blood chemistry, skin conductance, eating behavior, craving, and body image. An improvement is also expected for the values in the applied psychophysiological tests, the cognitive performance, as well as the eating behavior and physical activities of the participants.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This study has two arms, experimental and control group. The first one will receive the treatment and the control group that does not receive it until the intervention group completes the treatment. Both groups will be measured before and after completion, with three months follow-up
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
The participants will not be notified about the intervention group or the control group and will be randomly assigned. The procedures of this study will be available only to the researchers, therapists, and the bioethics committee of the Autonomous University of Ciudad Juárez

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Cognitive remediation therapy and multidisciplinary intervention

The participants (obese adults) in the experimental group will receive treatment with cognitive remediation therapy, nutritional and physical activity instruction through 18 weekly sessions of intervention.

Group Type EXPERIMENTAL

Cognitive remediation therapy and multidisciplinary intervention

Intervention Type BEHAVIORAL

The Randomized Controlled Trial will comprise of multidisciplinary intervention and remediation cognitive therapy which will be conducted with obese diagnosed adults of 19-60 years old. The enrolled patients will be randomized in a two-arm control trial with repeated measures and follow-up of three months. The experimental group participants will receive the intervention, while the control group remains on a waiting list.

Nutritional and physical activity plus cognitive remediation therapy sessions to improve the thoughts style, problem-solving, planning and organization, the emotions and body image are included

Control

The control group participants will not receive the treatment until the experimental group participants complete the intervention and carry out the measurements

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Cognitive remediation therapy and multidisciplinary intervention

The Randomized Controlled Trial will comprise of multidisciplinary intervention and remediation cognitive therapy which will be conducted with obese diagnosed adults of 19-60 years old. The enrolled patients will be randomized in a two-arm control trial with repeated measures and follow-up of three months. The experimental group participants will receive the intervention, while the control group remains on a waiting list.

Nutritional and physical activity plus cognitive remediation therapy sessions to improve the thoughts style, problem-solving, planning and organization, the emotions and body image are included

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Ages 19-60
* BMI \>30
* BFP \>25 (women)
* BFP \>32 (Men)
* High waist circumference \>88 cm (women)
* High waist circumference \>94 cm (men)
* Signed informed consent

Exclusion Criteria

* If the participant is enrolled in a weight control or physical exercise program.
* If the participant is under any medical psychological treatment
* If the participant is presenting any eating disorder, a thyroid or neurological diseases
* Pregnant women
* Unfinished procedures
* Less than 20% of assistance during the intervention
Minimum Eligible Age

19 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Universidad Autonoma de Ciudad Juarez

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Loya Yolanda, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidad Autónoma de CIudad Juárez

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Graciela C Avitia, PhD

Role: CONTACT

6882100 ext. 3653

ANA G GARCIA, MA

Role: CONTACT

6882100 ext. 3688

References

Explore related publications, articles, or registry entries linked to this study.

Smith E, Hay P, Campbell L, Trollor JN. A review of the association between obesity and cognitive function across the lifespan: implications for novel approaches to prevention and treatment. Obes Rev. 2011 Sep;12(9):740-55. doi: 10.1111/j.1467-789X.2011.00920.x. No abstract available.

Reference Type BACKGROUND
PMID: 21991597 (View on PubMed)

ALAD (2019). Latin American Diabetes Association. ALAD Guidelines concerning the Diagnosis, Control and Treatment of Type 2 Mellitus Diabetes with Medicine based on Evidence 2019 Edition. Latin American Diabetes Association Magazine ISSN: 2248-6518 México: Permanyer https://www.revistaalad.com/guias/5600AX191_guias_alad_2019.pdf

Reference Type BACKGROUND

Allom V, Mullan B, Smith E, Hay P, Raman J. Breaking bad habits by improving executive function in individuals with obesity. BMC Public Health. 2018 Apr 16;18(1):505. doi: 10.1186/s12889-018-5392-y.

Reference Type BACKGROUND
PMID: 29661241 (View on PubMed)

Batterink L, Yokum S, Stice E. Body mass correlates inversely with inhibitory control in response to food among adolescent girls: an fMRI study. Neuroimage. 2010 Oct 1;52(4):1696-703. doi: 10.1016/j.neuroimage.2010.05.059. Epub 2010 May 25.

Reference Type BACKGROUND
PMID: 20510377 (View on PubMed)

Cabas Hoyos, K., González Bracamonte Y. and Mendoza Álvarez C. (2017). Executive Functioning and Depression in college students with normoweight, overweight and obesity Type 1. Psychological Reports 18 (1) 133-144 https://doi.org/10.18566/infpsic.v18n1a07

Reference Type BACKGROUND

Camacho Laraña, M., Alcalá Pérez, V. and Alcalá S.N. (2020). Gender differences in patients with morbid obesity tributary to bariatric surgery. Psychopathology and Clinical Psychology Magazine. ISSN: 1136-5420 doi:10.5944/rppc.vol.20.number.3.2015.15892 Spain: Spanish Association of Clinical Psychology and Psychopathology

Reference Type BACKGROUND

Carretero Gomez J, Ena J, Arevalo Lorido JC, Segui Ripoll JM, Carrasco-Sanchez FJ, Gomez-Huelgas R, Perez Soto MI, Delgado Lista J, Perez Martinez P; en representacion del grupo de trabajo de Diabetes, Obesidad y Nutricion de la Sociedad Espanola de Medicina Interna. Obesity is a chronic disease. Positioning statement of the Diabetes, Obesity and Nutrition Workgroup of the Spanish Society of Internal Medicine (SEMI) for an approach centred on individuals with obesity. Rev Clin Esp. 2020 Jul 25:S0014-2565(20)30180-6. doi: 10.1016/j.rce.2020.06.008. Online ahead of print. English, Spanish.

Reference Type BACKGROUND
PMID: 32723530 (View on PubMed)

Chao A, Grilo CM, White MA, Sinha R. Food cravings, food intake, and weight status in a community-based sample. Eat Behav. 2014 Aug;15(3):478-82. doi: 10.1016/j.eatbeh.2014.06.003. Epub 2014 Jun 18.

Reference Type BACKGROUND
PMID: 25064302 (View on PubMed)

Dohle S, Diel K, Hofmann W. Executive functions and the self-regulation of eating behavior: A review. Appetite. 2018 May 1;124:4-9. doi: 10.1016/j.appet.2017.05.041. Epub 2017 May 25.

Reference Type BACKGROUND
PMID: 28551113 (View on PubMed)

Flores Lázaro, J.C., OstroskyShejet, F. and Gutiérrez Loxano, A. (2014). Neuropsychological Development of frontal lobes and executive functions. Editorial/Publisher: The Modern Manual México

Reference Type BACKGROUND

Gómez Puente, J.M. y Martínez Marcos, M. (2017). Overweight and Obesity: Efficiency of interventions in adults. Clinical Nursing 28(1) 65-74 ISSN: 1130-8621 Spain: Elsevier https: doi.org/10.1016/j.enfcli.201 7.06.005

Reference Type BACKGROUND

González, M. (2018). Role of executive functions in comprehending food intake. Answers or voids? Gastroenterology Venezuelan Society Magazine Vol.72 Númber 2 pages 38-43 ISSN: 2477-975X On line: https://www.researchgate.net/publication/334045971_Rol_de_las_funcion

Reference Type BACKGROUND

Guarch Domènech, J. y Navarro Odriozola, V. (2016) Cognitive Psychotherapies. Biological Psychiatry. 23 (S1): 40-45 ISSN: 1134-5934 Spain: Elsevier and Spanish Society of Biological Psychiatry.

Reference Type BACKGROUND

Hernández Sampieri, R., Fernández Collado, C., y Baptista Lucio, P. (2014). Methodology of Research. México: Trillas Publisher/Editorial

Reference Type BACKGROUND

INSP National Institute of Public Health. Results Report of the National Health and Nutrition Survey (ENSANUT) 2018. México: National Institute of Public Health. On Line: https://ensanut.insp.mx/encuestas/ensanut2018/informes.php

Reference Type BACKGROUND

Lafuente, M.D. (2012). Cognitive Behavioral Treatment of Obesity Eating Behavior Disorders (14) 1490-1504 ISSN: 1699-7611 Spain: Behavioral Sciences Institute On Line: https://dialnet.unirioja.es/servlet/articulo?codigo=6250628

Reference Type BACKGROUND

Marin-Soto MD, Leon CV, Perez-Vielma NM, Castillo-Ramirez M, Miliar-Garcia A, Murillo-Tovar MM, Mendez-Pena B, Aguilera-Sosa VR. Intense craving for appetizing foods: validation and standardization of the Food Cravings Questionnaire-Trait in Mexico. Gac Med Mex. 2020;156(1):27-33. doi: 10.24875/GMM.19005358.

Reference Type BACKGROUND
PMID: 32026878 (View on PubMed)

Meza Peña, C. y Pompa-Guajardo, E.G. (2016). Gender, obesity and self-concept in a teen sample in México. Sports Sciences International Magazine 44 (12) 137-148. ISSN:1885-3137 Spain: Editorial/Publisher Ramón Cantó Alcaraz On Line: http://www.redalyc.org/articulo.oa?id=71044746005

Reference Type BACKGROUND

Navarro Santos, F. (2014) Body Image Construction for Overweight Women. Guillén Riebeling, The Modern Manual, A.S. of V.C.

Reference Type BACKGROUND

Polo García, D. (2014). Relationship between food anxiety constructos, impulsiveness and sensibility towards the rewards in a college population (master's thesis) Jaén College, Andalucía, Spain.

Reference Type BACKGROUND

Raman J, Hay P, Smith E. Manualised Cognitive Remediation Therapy for adult obesity: study protocol for a randomised controlled trial. Trials. 2014 Nov 4;15:426. doi: 10.1186/1745-6215-15-426.

Reference Type BACKGROUND
PMID: 25370364 (View on PubMed)

Raman J, Hay P, Tchanturia K, Smith E. A randomised controlled trial of manualized cognitive remediation therapy in adult obesity. Appetite. 2018 Apr 1;123:269-279. doi: 10.1016/j.appet.2017.12.023. Epub 2017 Dec 24.

Reference Type BACKGROUND
PMID: 29278718 (View on PubMed)

Ramírez Molina, M.J. (2017). Body Image, body satisfaction, specific auto-efficiencies and risk and health behaviors to improve body image (doctoral thesis). University of Granada, Granada Spain. https://hera.ugr.es/tesisugr/26765640.pdf

Reference Type BACKGROUND

Ríos Saldaña, M.R. Rodríguez Soriano, N.Y. and Álvarez Gasca, M.A. (2014). Incidence of Obesity, risks factors and emotional problems in college students. Psychology of Obesity Life Spheres Multidiscipline and complexity 63-74 México: The Modern Manual, A.S of V.C.

Reference Type BACKGROUND

Risco, L. y Aros, C. (2019). Mood, nutrition and craving disorders. Chilean Journal of neuropsychiatry. 57 (30) 295-305 ISSN: 0717:9227 Chile: Neurology, Psychiatry and Neurology Society.

Reference Type BACKGROUND

Salvador Castell, G., Serra Majem, L. and Ribas Barba, L. (2015). What and how much do we eat? The 24 hour remember method. Spanish Magazine for Community Nutrition 21 (Suppl. 1): 42-44 ISSN: 1135-3074 Spain: Spanish Society for Community Nutrition and Latin american Group for Community Nutrition. Doi10.14642/RENC.2015.21.sup1.5049

Reference Type BACKGROUND

Segura, M., Roncero, M., Oltra Cucarella, J., Blasco, L., Ciscar, S., Portillo, M., Malea, A., Espert, R. y Perpiñá, C. (2017). Cognitive remediation Training and emotional abilities in a group format for patients with obesity: A pilot study. Psychopathology and Clinical Psychology Magazine. Vol.22 127-138 doi: 10.5944/rppc

Reference Type BACKGROUND

Shama Levy, T., Villalpando-Hernández, S. y Rivera-Dommarco, J. (2006). Procedure's Manual for nutrition projects. Public Health National Institute. On line: http://www.salud.gob.mx/unidades/cdi/documentos/proy_nutricion.pdf

Reference Type BACKGROUND

Smith, E., Hay, P. y Raman, J. (2014). Cognitive Remediation Therapy for obesity. En Tchanturia, K. Cognitive Remediation Therapy (CRT) for Eating and Weigth Disorders 176-190 England: Routledge

Reference Type BACKGROUND

Sociedad Mexicana de Psicología, Código ético del psicólogo. [Mexican Society of Psychology (2010). Ethical Code for the Psychologist México], Trillas, Ciudad de México, México

Reference Type BACKGROUND

Tchanturia, K., Davies, H., Reeder, C. y Wykes, T., (2012). Cognitive Remediation Therapy for Anorexia Nervosa. Translation by López, C., Escobar, T. and Carral, L.

Reference Type BACKGROUND

Genders R, Tchanturia K. Cognitive remediation therapy (CRT) for anorexia in group format: a pilot study. Eat Weight Disord. 2010 Dec;15(4):e234-9. doi: 10.1007/BF03325304.

Reference Type BACKGROUND
PMID: 21406946 (View on PubMed)

Torres V, Castro Sanchez AM, Mataran Penarocha GA, Lara Palomo I, Aguilar Ferrandiz ME, Moreno Lorenzo C. [Benefits of cognitive behavior therapy and acupressure therapy in obese patients: a randomized clinical trial]. Nutr Hosp. 2011 Sep-Oct;26(5):1018-24. doi: 10.1590/S0212-16112011000500015. Spanish.

Reference Type BACKGROUND
PMID: 22072347 (View on PubMed)

Vázquez Arévalo, R., Galán Julio, J., López Aguilar, X., Alvarez Rayón, G.L., Marcilla Díaz, J.M., Caballero Romo, A. and Unikel Santoncini C. (2011). Validity of Body Shape Questionnaire (BSQ) in Mexican Women. Mexican Magazine for Eating Disorders Vol. 2 pages. 45-52 ISSN: 2007-1523 México: Autonomous National University of México

Reference Type BACKGROUND

Verdejo-Garcia A, Bechara A. [Neuropsychology of executive functions]. Psicothema. 2010 May;22(2):227-35. Spanish.

Reference Type BACKGROUND
PMID: 20423626 (View on PubMed)

Weschler, D. (2013). WAIS-IV Weschler's Intelligence Scale ISBN: 91-100 México: The Modern Manual.

Reference Type BACKGROUND

WHO World Health Organization. 10 facts about obesity. On Line: https://www.who.int/features/factfiles/obesity/es/, https://www.who.int/es/news- room/fact-sheets/detail/obesity-and-overweight

Reference Type BACKGROUND

WHO World Health Organization. GPAQ Analysis Guide On Line: https://www.who.int/ncds/surveillance/steps/resources/GPAQ_Analysis_Guide.pdf

Reference Type BACKGROUND

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CIEB-2019-2-53

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Health and Wellness in Obesity
NCT02102061 UNKNOWN NA