Imagery Rescripting and Imaginal Exposure for Anxiety Symptoms

NCT ID: NCT05292807

Last Updated: 2022-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

460 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-14

Study Completion Date

2025-01-31

Brief Summary

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This study will recruit 460 participants who self-report high symptoms of anxiety. Participants will be randomly assigned to one of 4 groups: one analog intervention of Imagery Rescripting (IR) for memories, an analog intervention of IR for future events, and analog intervention of Imaginal Exposure (IE) for memories and an analog intervention of IE for future events. We will examine the efficacy and mechanisms behind each intervention.

Detailed Description

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After being informed about the study potential risks, all patients giving written informed consent will undergo screening to determine eligibility for study entry. They will be randomly assigned to one of four conditions (Imagery rescripting past; Imagery rescripting future; Imaginal exposure past; Imaginal exposure future) at a 1:1:1:1 ratio (n = 115 per group). Participant will be assigned using a variance minimization method that controls for between group variance in continuous and categorical variables- SPIN, ASI-3, OCI-R, GAD-7 and gender with a completely random assignment p random = .2 (for algorithm see Sella et al., 2018). Participants will attend three \~1.5 hour online ZOOM sessions (baseline-assessment and measurement, intervention, post assessment and measurement and follow-up measurement).

In this multiple baseline study, participant will enter the intervention phase either 7 or 14 days after the baseline stage.

Assessors will be blind to the treatment condition.

Conditions

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Social Anxiety Generalized Anxiety Obsessive-Compulsive Symptom Panic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Imaginal exposure for memories

A behavioral intervention in imagery for memories

Group Type EXPERIMENTAL

Imaginal exposure for memories

Intervention Type BEHAVIORAL

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a past distressing anxiety provoking scenario multiple times while honing in on the most negative aspects.

Imaginal exposure for future events

A behavioral intervention in imagery for future events

Group Type EXPERIMENTAL

Imaginal exposure for future events

Intervention Type BEHAVIORAL

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a future distressing anxiety provoking scenario multiple times while honing in on the most negative aspects.

Imagery rescripting for memories

A different behavioral intervention in imagery for memories

Group Type EXPERIMENTAL

Imagery rescripting for memories

Intervention Type BEHAVIORAL

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a past distressing anxiety provoking scenarios one time while honing in on the most negative aspects. Afterwards they will insert changes into the script that try to help them cope in the imagery: First imagining the scenario from a different character perspective that enacts changes in the memories. Second, The will imagine the scenario again from the original perspective along with changes done by the additional character.

Imagery rescripting for future events

A different behavioral intervention in imagery for future events

Group Type EXPERIMENTAL

Imagery rescripting for future events

Intervention Type BEHAVIORAL

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a future distressing anxiety provoking scenarios one time while honing in on the most negative aspects. Afterwards they will insert changes into the script that try to help them cope in the imagery: First imagining the scenario from a different character perspective that enacts changes in the memories. Second, The will imagine the scenario again from the original perspective along with changes done by the additional character.

Interventions

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Imaginal exposure for memories

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a past distressing anxiety provoking scenario multiple times while honing in on the most negative aspects.

Intervention Type BEHAVIORAL

Imaginal exposure for future events

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a future distressing anxiety provoking scenario multiple times while honing in on the most negative aspects.

Intervention Type BEHAVIORAL

Imagery rescripting for memories

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a past distressing anxiety provoking scenarios one time while honing in on the most negative aspects. Afterwards they will insert changes into the script that try to help them cope in the imagery: First imagining the scenario from a different character perspective that enacts changes in the memories. Second, The will imagine the scenario again from the original perspective along with changes done by the additional character.

Intervention Type BEHAVIORAL

Imagery rescripting for future events

Participants in this arm will be asked to decide alongside with the intervention provider (a clinical PhD student or M.A student under the supervision of the principal investigator) to imagine a script based on a future distressing anxiety provoking scenarios one time while honing in on the most negative aspects. Afterwards they will insert changes into the script that try to help them cope in the imagery: First imagining the scenario from a different character perspective that enacts changes in the memories. Second, The will imagine the scenario again from the original perspective along with changes done by the additional character.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

We will recruit participants based on attainment of SPIN score \>= 24 and/or ASI-3 scores \>=23 and/or OCI-R subscale scores (not including hoarding subscale) \>=6 and/or GAD-7 scores \>= 9 .

Exclusion Criteria

Diagnosis of psychosis, active suicidality, post-traumatic stress disorder, acute stress disorder. Can't report a negative imagery related to a future social scenario. Attending active psychotherapy sessions. Started/stopped taking psychotherapeutic medications in the last 3 months.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hebrew University of Jerusalem

OTHER

Sponsor Role lead

Responsible Party

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Jonathan D. Huppert

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jonathan D Huppert, PhD

Role: PRINCIPAL_INVESTIGATOR

Professor in the Hebrew University of Jerusalem psychology department

Locations

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Hebrew University of Jerusalem

Jerusalem, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Snir Barzilay, PhD. student

Role: CONTACT

+972 50 4499 435

Jonathan D Huppert, PhD

Role: CONTACT

Facility Contacts

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Jonathan Huppert, PhD

Role: primary

+97225883376

References

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Other Identifiers

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isf2157/2021

Identifier Type: -

Identifier Source: org_study_id

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