Cartilage Versus Temporalis Fascia Graft in Tympanoplasty for Recurrent Tympanic Membrane Perforation '' Comparative Study ''

NCT ID: NCT05282810

Last Updated: 2022-03-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

26 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-30

Study Completion Date

2023-05-31

Brief Summary

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Use of Cartilage Versus Temporalis Fascia as a Graft in Tympanoplasty for Recurrent Tympanic Membrane Perforation

Detailed Description

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The main aim of successful tympanoplasty is to create a well aerated closed cavity after total removal of the disease. Numerous types of grafting materials have been used for closure of the tympanic membrane including fascia, periosteum, perichondrium, cartilage, vein, skin, and fat tissue . Autografts are thought to be the most compatible grafting materials with the best surgical results in tympanoplasty Temporal muscle fascia is composed of irregularly arranged elastic fibers and fibrous connective tissue. For this reason postoperative dimensions of temporal muscle fascia are unpredictable.

Cartilage has a constant shape, firmer than fascia and also lack fibrous tissue, so that postoperative dimensions remains the same and beside this, it is also nourished by diffusion and show great adaptation with TM . These advantages make the cartilage graft more preferable by otologists recently.

the use of cartilage graft in many different ways such as perichondrium cartilage island technique, palisade technique or cartilage reinforcement technique

Conditions

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Tympanic Membrane Perforation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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cartilage tympanoplasty

use cartilage in tympanoplasty for recuurent perforation

tympanoplasty

Intervention Type OTHER

use of cartilage versus tempotalis fascia in tympanoplasty for recuurent perforation

temporalis fascia graft in tympanoplasty

use temporalis fascia as a graft in tympanoplasty for recuurent perforation

tympanoplasty

Intervention Type OTHER

use of cartilage versus tempotalis fascia in tympanoplasty for recuurent perforation

Interventions

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tympanoplasty

use of cartilage versus tempotalis fascia in tympanoplasty for recuurent perforation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with safe chronic suppurative otitis media patient with recurrent perforation patirnt with coductive hearing loss

Exclusion Criteria

* sensorineural hearing loss active infection compromised immune system
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Caroleen Mounir Tawfik

researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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caroleen mounir, researcher

Role: CONTACT

01206045590

hamza el shafey ahmed, doctor

Role: CONTACT

References

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Jalali MM, Motasaddi M, Kouhi A, Dabiri S, Soleimani R. Comparison of cartilage with temporalis fascia tympanoplasty: A meta-analysis of comparative studies. Laryngoscope. 2017 Sep;127(9):2139-2148. doi: 10.1002/lary.26451. Epub 2016 Dec 9.

Reference Type BACKGROUND
PMID: 27933630 (View on PubMed)

Shakya D, Nepal A. Long-term results of type I tympanoplasty with perichondrium reinforced cartilage palisade vs temporalis fascia for large perforations: A retrospective study. J Otol. 2021 Jan;16(1):12-17. doi: 10.1016/j.joto.2020.07.004. Epub 2020 Jul 29.

Reference Type BACKGROUND
PMID: 33505444 (View on PubMed)

Other Identifiers

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recurrent tympanoplasty

Identifier Type: -

Identifier Source: org_study_id

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