Joint Thoracic Oncology Research Unit of LYon: Lung cancerS DatabaSE (ULYSSE)

NCT ID: NCT05267041

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

4000 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-05

Study Completion Date

2042-05-05

Brief Summary

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Prospective longitudinal cohort associated to blood collection, pathological samples collection, and radiological and pathological imaging collection.

Detailed Description

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Conditions

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Lung Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

One questionnaire between diagnostic annoucement and first line treatement One 6 months later One before second line treatment One 6 months later after second line treatment Optionnal Veinous Blood Sample (28 mL) between the diagnostic annoucement and the first line of treatment
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Cohort of Adults with lung cancer

Patients newly diagnosed with lung cancer.

Group Type EXPERIMENTAL

Blood sample

Intervention Type BIOLOGICAL

One optional veinous blood sampling (24 ML) between the first diagnostic annoucement and before the first treatment for lung cancer

Questionnaire

Intervention Type OTHER

to collect data not reported in the patient's medical file, such as passive smoking, family history of cancer, and attempts to quit smoking.

Interventions

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Blood sample

One optional veinous blood sampling (24 ML) between the first diagnostic annoucement and before the first treatment for lung cancer

Intervention Type BIOLOGICAL

Questionnaire

to collect data not reported in the patient's medical file, such as passive smoking, family history of cancer, and attempts to quit smoking.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient treated for a thoracic cancer in the Lyon University Hospital: non-small cell lung cancer, small cell lung cancer, mesothelioma…
* Diagnosis can be done:

* By cytology or pathologic assessment
* Or by multidisciplinary team meeting decision:

* Irradiation without morpho-metabolic sampling
* Treatment without sampling based on non-invasive molecular data

Exclusion Criteria

\- Refusal to participate

For optional blood sampling :

* \< 30 kg for blood collection
* No blood sampling schedule for care
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre Hospitalier Lyon Sud

Pierre-Bénite, , France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Sébastien COURAUD, PhD

Role: primary

0478863718 ext. +33

Other Identifiers

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69HCL21_1175

Identifier Type: -

Identifier Source: org_study_id

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