Survey on Lymphedema After Sentinel Lymph Node Biopsy in People With Cervical or Vulvar Cancer

NCT ID: NCT05255393

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

111 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-15

Study Completion Date

2025-11-19

Brief Summary

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The purpose of this study is to collect information that may identify people who are at risk of developing lower extremity lymphedema (LEL) after sentinel lymph node biopsy (SLN) during surgery for early-stage vulvar or cervical cancer, and to improve the quality and accuracy of the information that is given to people who have this procedure.

Please note that, during this study, the researchers will collect information from a questionnaire completed by people who had SLN and LND+/- SLN during surgery for early-stage cervical or vulvar cancer. No form of treatment will be provided as part of the study, and no investigational tests or procedures will be performed.

Detailed Description

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Conditions

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Cervical Cancer Vulvar Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Standard lymphadenectomy(LND) with sentinel lymph node mapping (SLN)

Patients will receive up to two mailings or messages and two phone calls if they do not respond. Self-addressed, stamped envelopes will be provided for return of questionnaires.

No other interventions are planned.

Questionnaires

Intervention Type OTHER

A 13-item questionnaire specific to LEL, developed and validated by investigators at the Mayo Clinic.

The EORTC QLQ-C30 is a 30-item questionnaire designed to assess the quality of life of cancer patients.

The EORTC Quality of Life - Cervical Cancer Module.

Standard lymphadenectomy(LND) alone

Patients will receive up to two mailings or messages and two phone calls if they do not respond. Self-addressed, stamped envelopes will be provided for return of questionnaires.

No other interventions are planned.

Questionnaires

Intervention Type OTHER

A 13-item questionnaire specific to LEL, developed and validated by investigators at the Mayo Clinic.

The EORTC QLQ-C30 is a 30-item questionnaire designed to assess the quality of life of cancer patients.

The EORTC Quality of Life - Cervical Cancer Module.

Interventions

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Questionnaires

A 13-item questionnaire specific to LEL, developed and validated by investigators at the Mayo Clinic.

The EORTC QLQ-C30 is a 30-item questionnaire designed to assess the quality of life of cancer patients.

The EORTC Quality of Life - Cervical Cancer Module.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Presented to MSK with newly diagnosed early-stage cervical cancer of any histologic profile or early stage vulvar cancer of any histologic profile.

°Early stage: Stage 1-2
* Underwent primary surgery at our institution between January 2006 and January 2022.
* Alive at the time of study activation
* English comprehension
* Capable of providing informed consent

Exclusion Criteria

* Had documented macroscopic evidence of metastatic disease at the time of initial diagnosis
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Memorial Sloan Kettering Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mario Leitao, MD

Role: PRINCIPAL_INVESTIGATOR

Memorial Sloan Kettering Cancer Center

Locations

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Memorial Sloan Kettering Cancer Center

New York, New York, United States

Site Status

Countries

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United States

Related Links

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http://www.mskcc.org/mskcc/html/44.cfm

Memorial Sloan Kettering Cancer Center

Other Identifiers

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22-002

Identifier Type: -

Identifier Source: org_study_id

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